Evidence map›Paper›PMID 38225218›Full record

Trial reportJournal of cachexia, sarcopenia and muscle2024

Exercise training response according to baseline ferrokinetics in heart failure with preserved ejection fraction: A substudy of the TRAINING-HF trial.

Patricia Palau, Laura López, Eloy Domínguez, Rafael de La Espriella, Raquel Campuzano, Almudena Castro, Gema Miñana, Agustin Fernández-Cisnal, Juan Sanchis, Julio Núñez

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Patricia PalauDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Laura LópezDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Eloy DomínguezDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Rafael de La EspriellaDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Raquel CampuzanoDepartment of Cardiology, Hospital Universitario Fundación de Alcorcón, Madrid, Spain.
Almudena CastroDepartment of Cardiology, Hospital Universitario La Paz, Madrid, Spain.
Gema MiñanaDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Agustin Fernández-CisnalDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Juan SanchisDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Julio NúñezDepartment of Cardiology, Hospital Clínico Universitario, INCLIVA. Universitat de València, Valencia, Spain.
Universitat de València · ESHospital Universitario Fundación Alcorcón · ESHospital Universitario La Paz · ESUniversitat Jaume I · ES

Funding

CIBER Cardiovascular 16/11/00403CIBER Cardiovascular 16/11/00420CIBER Cardiovascular 16/11/00486Sociedad Española de Cardiología, Investigacion Clınica en Cardiologıa SEC 2015Spanish Clinical Research Network (SCReN) PT17/0017/0003Spanish Clinical Research Network (SCReN) PT20/00100Unidad de Investigación Clínica y Ensayos Clínicos INCLIVA Health Research Institute
6 · The paper itself

Abstract

backgroundIron deficiency (ID) is associated with impaired functional capacity in patients with heart failure (HF), even in those with preserved ejection fraction (HFpEF). This study aimed to evaluate the effect of baseline ferrokinetics on peak oxygen consumption (peakVO

methodsThis study is a post-hoc sub-analysis of a randomized clinical trial in which 59 stable patients with HFpEF were randomized to receive a 12-week programme of inspiratory muscle training (IMT), functional electrical stimulation (FES), IMT + FES or usual care (UC) to evaluate change in peakVO

resultsThe mean age was 74 ± 9 years, and 36 (61%) had ID. The mean of peakVO

conclusionsFerrokinetics status plays an essential role in modifying the aerobic capacity response to physical therapies in patients with HFpEF. Further studies are required to confirm these findings.

Indexed as

Heart FailureIron DeficienciesAgedAged, 80 and overExerciseFerritinsHumansStroke VolumeTransferrinsFerritinsTransferrinsAerobic capacityHeart failure with preserved ejection fractionIron deficiencypeakVO2Physical therapies

Identifiers

PMID38225218
PMCPMC10995251
OpenAlexW4390917537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.