Evidence map›Paper›PMID 38224842›Full record

ReviewVirus research2024

Oropouche virus: A neglected global arboviral threat.

Yuli Zhang, Xiao Liu, Zhen Wu, Shuo Feng, Ke Lu, Wenbing Zhu, Hengyi Sun, Guoyu Niu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Virus research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 5 pooled it
37.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 5 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Review
  7. Article
  8. Detection of a novel ShamondaEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Five Hot Topics in Tropical Medicine: 2025.Infectious disease reports · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Observational
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuli ZhangShandong Second Medical University, Weifang, 261053, China.
Xiao LiuShandong Second Medical University, Weifang, 261053, China.
Zhen WuShandong Second Medical University, Weifang, 261053, China.
Shuo FengShandong Second Medical University, Weifang, 261053, China.
Ke LuShandong Second Medical University, Weifang, 261053, China.
Wenbing ZhuShandong Second Medical University, Weifang, 261053, China.
Hengyi SunShandong Second Medical University, Weifang, 261053, China. Electronic address: Sunhengyi1987@wfmc.edu.cn.
Guoyu NiuShandong Second Medical University, Weifang, 261053, China. Electronic address: niugy@wfmc.edu.cn.
Weifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Oropouche virus is an important arthropod-borne virus in the Peribunyaviridae family that can cause febrile illnesses, and it is widely distributed in tropical regions such as Central and South America. Since the virus was first identified, a large number of related cases are reported every year. No deaths have been reported to date, however, the virus can cause systemic infections, including the nervous and blood systems, leading to serious complications. The transmission of Oropouche virus occurs through both urban and sylvatic cycles, with the anthropophilic biting midge Culicoides paraensis serving as the primary vector in urban areas. Direct human-to-human transmission of Oropouche virus has not been observed. Oropouche virus consists of three segments, and the proteins encoded by the different segments enables the virus to replicate efficiently in the host and to resist the host's immune response. Phylogenetic analyses showed that Oropouche virus sequences are geographically distinct and have closer homologies with Iquitos virus and Perdoes virus, which belong to the family Peribunyaviridae. Despite the enormous threat it poses to public health, there are currently no licensed vaccines or specific antiviral treatments for the disease it causes. Recent studies have utilised imJatobal virusmunoinformatics approaches to develop epitope-based peptide vaccines, which have laid the groundwork for the clinical use of vaccines. The present review focuses on the structure, epidemiology, immunity and phylogeny of Oropouche virus, as well as the progress of vaccine development, thereby attracting wider attention and research, particularly with regard to potential vaccine programs.

Indexed as

ArbovirusesBunyaviridae InfectionsOrthobunyavirusVaccinesHumansPhylogenyVaccinesEpidemiologyEvolutionaryImmunityOropouche virusStructureVaccine development

Identifiers

PMID38224842
PMCPMC10827532
OpenAlexW4390919531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.