Evidence map›Paper›PMID 38224447›Full record

ArticleProbiotics and antimicrobial proteins2025

Effects of Metabolites of Lactobacillus casei on Expression and Neutralization of Shiga Toxin by Enterohemorrhagic Escherichia coli.

Arpita Aditya, Zajeba Tabashsum, Zabdiel Alvarado Martinez, Debabrata Biswas

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arpita AdityaDepartment of Animal Sciences, University of Maryland, College Park, MD, 20742, USA.
Zajeba TabashsumBiological Sciences Program, University of Maryland, College Park, MD, 20742, USA.
Zabdiel Alvarado MartinezBiological Sciences Program, University of Maryland, College Park, MD, 20742, USA.
Debabrata BiswasDepartment of Animal Sciences, University of Maryland, College Park, MD, 20742, USA. dbiswas@umd.edu.

Funding

USDA-National Institute of Food and Agriculture 20185110628809
6 · The paper itself

Abstract

Shiga toxin (stx), produced by enterohemorrhagic Escherichia coli (EHEC) or Shigella, causes hemolytic uremic syndrome (HUS) in humans. EHEC-mediated illnesses are recommended to treat by immune supportive strategies, instead of antibiotic therapy. Widely used probiotic Lactobacillus casei produces many bioactive metabolites, i.e., conjugated linoleic acids (CLAs) which have potential to educate host immunity and control EHEC growth and expression of its virulence genes. In this study, it was found that total metabolites of L. casei exerted a protective effect on Gb

Indexed as

Enterohemorrhagic Escherichia coliLacticaseibacillus caseiProbioticsShiga ToxinAnimalsEscherichia coli InfectionsHumansShiga ToxinConjugated linoleic acidEHECMetabolitesProbioticsShiga toxin

Identifiers

PMID38224447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.