Evidence map›Paper›PMID 38224421›Full record

ArticleForensic science, medicine, and pathology2024

Death due to sickle cell crisis: a case report.

Teaghan Koster, Elizabeth Boyer, David J Clutterbuck, Hadas Benhabib, Jayantha Herath

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Forensic science, medicine, and pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Teaghan KosterDepartment of Pathology and Molecular Medicine, Queen's University, 76 Stuart St, Kingston, ON, K7L 2V7, Canada. t.koster@queensu.ca.ORCID http://orcid.org/0009-0005-7938-2674
Elizabeth BoyerUniversity of Nebraska Medical Center, Omaha, USA.
David J ClutterbuckProvincial Forensic Pathology Unit, Ontario Forensic Pathology Service, 25 Morton Shulman Avenue, Toronto, ON, M3M 0B1, Canada.
Hadas BenhabibDepartment of Medical Imaging, University of Toronto, 263 McCaul St 4th Floor, Toronto, ON, M5T 1W7, Canada.
Jayantha HerathProvincial Forensic Pathology Unit, Ontario Forensic Pathology Service, 25 Morton Shulman Avenue, Toronto, ON, M3M 0B1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell disease (SCD) is the most common hereditary hemoglobinopathy worldwide. It results in characteristic acute and chronic findings on postmortem computed tomography (PMCT), macroscopic and microscopic examinations. While the diagnostic imaging and macroscopic features are not specific for SCD on their own, when coupled with microscopic features such as sickled erythrocytes and evidence of chronic venous congestion (i.e., Gamna-Gandy bodies), these clues can help alert forensic pathologists to the presence of SCD. Despite the prevalence of the disease and the constellation of findings alluded to above, SCD is not often explored in forensic pathology literature. This case demonstrates classic acute and chronic features of SCD on PMCT, macroscopic and microscopic examinations. It explores the pathophysiology leading to sudden and unexpected death in a person with SCD and possible pitfalls in attribution of cause of death.

Indexed as

Anemia, Sickle CellAdultDeath, SuddenFatal OutcomeFemaleHumansMaleTomography, X-Ray ComputedAutosplenectomyForensic pathologyGamna-Gandy bodiesSickle cell crisisSickle cell diseaseSickle cell traitThrombi

Identifiers

PMID38224421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.