Evidence map›Paper›PMID 38224377›Full record

ArticleEuropean radiology2024

Wall permeability on magnetic resonance imaging is associated with intracranial aneurysm symptoms and wall enhancement.

Qichang Fu, Yi Zhang, Yong Zhang, Chao Liu, Jinyi Li, Meng Wang, Haiyang Luo, Jinxia Zhu, Feifei Qu, Mahmud Mossa-Basha and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Qichang FuDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, 1St Construction of E Rd, Two-Seven Districts, Zhengzhou, 450052, China.
Yi ZhangDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, 1St Construction of E Rd, Two-Seven Districts, Zhengzhou, 450052, China.
Yong ZhangDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, 1St Construction of E Rd, Two-Seven Districts, Zhengzhou, 450052, China.
Chao LiuDepartment of Interventional Neuroradiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jinyi LiDepartment of Interventional Neuroradiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Meng WangDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Haiyang LuoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jinxia ZhuMR Collaboration, Siemens Healthineers Ltd, Beijing, China.
Feifei QuMR Collaboration, Siemens Healthineers Ltd, Beijing, China.
Mahmud Mossa-BashaDepartment of Radiology, University of Washington School of Medicine, Seattle, WA, USA.
Sheng GuanDepartment of Interventional Neuroradiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jingliang ChengDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, 1St Construction of E Rd, Two-Seven Districts, Zhengzhou, 450052, China. fccchengjl@zzu.edu.cn.ORCID http://orcid.org/0000-0002-6996-329X
Chengcheng ZhuDepartment of Radiology, University of Washington School of Medicine, Seattle, WA, USA.
First Affiliated Hospital of Zhengzhou University · CNSiemens (China) · CNUniversity of Washington · US

Funding

Investigation of the quantitative intracranial aneurysm wall enhancement and geometric features associated with aneurysm volume growthR01HL162743 · NHLBI · UNIVERSITY OF WASHINGTON · PI Chengcheng Zhu · 2022 to 2026
$2.4M
Characterization of intracranial vessel wall morphology and inflammation using 3D high resolution MRIR00HL136883 · NHLBI · UNIVERSITY OF WASHINGTON · PI ZHU, CHENGCHENG · 2020 to 2022
$747k
NHLBI NIH HHS R00 HL136883NHLBI NIH HHS R01 HL162743
6 · The paper itself

Abstract

objectivesWall remodeling and inflammation accompany symptomatic unruptured intracranial aneurysms (UIAs). The volume transfer constant (K

methodsConsecutive patients with UIAs were prospectively recruited for 3-T DCE-MRI and VWI from January 2018 to March 2023. UIAs were classified as asymptomatic and symptomatic if associated with sentinel headache or oculomotor nerve palsy. K

resultsWe enrolled 82 patients with 100 UIAs (28 symptomatic and 72 asymptomatic). The median K

conclusionsK CLINICAL RELEVANCE STATEMENT: The volume transfer constant (K KEY POINTS: • The volume transfer constant is correlated with intracranial aneurysm symptoms and aneurysmal wall enhancement. • Dynamic contrast-enhanced and vessel wall MRI facilitates understanding of the pathophysiological characteristics of intracranial aneurysm walls. • The volume transfer constant and wall enhancement index perform better than the traditional PHASES score in differentiating symptomatic aneurysms.

Indexed as

Contrast MediaIntracranial AneurysmMagnetic Resonance ImagingAdultAgedFemaleHumansMaleMiddle AgedPermeabilityProspective StudiesContrast MediaInflammationIntracranial aneurysmMagnetic resonance imagingPermeabilityVessel wall

Identifiers

PMID38224377
PMCPMC11247137
OpenAlexW4390885741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.