Evidence map›Paper›PMID 38223896›Full record

ReviewGlobal challenges (Hoboken, NJ)2024

Biomedical Big Data Technologies, Applications, and Challenges for Precision Medicine: A Review.

Xue Yang, Kexin Huang, Dewei Yang, Weiling Zhao, Xiaobo Zhou

Abstract readReview
In one paragraph

Review in Global challenges (Hoboken, NJ), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. A Framework for Autonomous AI-Driven Drug Discovery.bioRxiv : the preprint server for biology · 2026
    Article
  6. Recent Advances in AI and GenAI for Health Informatics.Healthcare (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xue YangDepartment of Pancreatic Surgery and West China Biomedical Big Data Center West China Hospital Sichuan University Chengdu 610041 China.ORCID https://orcid.org/0000-0001-5846-5319
Kexin HuangDepartment of Pancreatic Surgery and West China Biomedical Big Data Center West China Hospital Sichuan University Chengdu 610041 China.
Dewei YangCollege of Advanced Manufacturing Engineering Chongqing University of Posts and Telecommunications Chongqing Chongqing 400000 China.
Weiling ZhaoCenter for Systems Medicine School of Biomedical Informatics UTHealth at Houston Houston TX 77030 USA.
Xiaobo ZhouCenter for Systems Medicine School of Biomedical Informatics UTHealth at Houston Houston TX 77030 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The explosive growth of biomedical Big Data presents both significant opportunities and challenges in the realm of knowledge discovery and translational applications within precision medicine. Efficient management, analysis, and interpretation of big data can pave the way for groundbreaking advancements in precision medicine. However, the unprecedented strides in the automated collection of large-scale molecular and clinical data have also introduced formidable challenges in terms of data analysis and interpretation, necessitating the development of novel computational approaches. Some potential challenges include the curse of dimensionality, data heterogeneity, missing data, class imbalance, and scalability issues. This overview article focuses on the recent progress and breakthroughs in the application of big data within precision medicine. Key aspects are summarized, including content, data sources, technologies, tools, challenges, and existing gaps. Nine fields-Datawarehouse and data management, electronic medical record, biomedical imaging informatics, Artificial intelligence-aided surgical design and surgery optimization, omics data, health monitoring data, knowledge graph, public health informatics, and security and privacy-are discussed.

Indexed as

biomedical big dataelectronic medical recordfederated learningknowledge graphmedical imaging analysisomics dataprecision medicine

Identifiers

PMID38223896
PMCPMC10784210

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.