Evidence map›Paper›PMID 38223849›Full record

ArticleEJVES vascular forum2024

The Impact of Intra-Operative Heparin on Thromboembolism and Death in a Matched Cohort of Patients with a Ruptured Abdominal Aortic Aneurysm.

Tiago F Ribeiro, Ricardo Correia, Rita Soares Ferreira, Frederico Bastos Gonçalves, Carlos Amaral, Maria Emília Ferreira

Abstract read
In one paragraph

Article in EJVES vascular forum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tiago F RibeiroHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.
Ricardo CorreiaHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.
Rita Soares FerreiraHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.
Frederico Bastos GonçalvesHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.
Carlos AmaralHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.
Maria Emília FerreiraHospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Portuguese nationwide estimates indicate that 20% of abdominal aortic aneurysms (AAAs) are treated when ruptured. In these cases, intra-operative unfractionated heparin (UFH) usage rates vary widely. Evidence on this topic is scarce and focused on patients treated by open repair (OSR). The aim was to determine the influence of UFH on peri-operative thromboembolic events (TEs) and death in a cohort of ruptured AAA (rAAA). Methods: Retrospective, single-centre, comparative study. From 2011 to April 2023, all consecutive rAAAs (endovascular repair [EVAR] and OSR) were considered. Primary outcomes were 30-day TE free survival and TE rates. The secondary outcome was 30-day death. Safety endpoints were procedural blood loss, blood product requirements, and secondary interventions due to haemorrhage. Using propensity score matching (PSM) each UFH patient was matched with one no UFH patient in a 1:1 ratio. Results: The study included 250 patients. After PSM, 190 patients were analysed (EVAR: 60.0% no-UFH vs. 64.4% UFH). TE free survival estimates favoured the UFH group (67.3% vs. 47.2%, Conclusion: In this cohort, intra-operative UFH was safe and associated with improved TE free survival, driven by a reduction in bowel ischaemia. Conversely, mortality remained unaffected. Randomised controlled trials are required to confirm these findings.

Indexed as

Abdominal aortic aneurysmEvent free survivalRuptured aortic aneurysmsThromboembolismUnfractionated heparin

Identifiers

PMID38223849
PMCPMC10784139

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.