Evidence map›Paper›PMID 38223684›Full record

ReviewPhenomics (Cham, Switzerland)2023

Phenomic Imaging.

Lizhen Lan, Kai Feng, Yudan Wu, Wenbo Zhang, Ling Wei, Huiting Che, Le Xue, Yidan Gao, Ji Tao, Shufang Qian and 4 more

Abstract readReview
In one paragraph

Review in Phenomics (Cham, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Genetic analysis of imaging-derived phenotypes.Nature reviews. Genetics · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Visual reading for [European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lizhen LanHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0001-6422-6963
Kai FengHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-1468-1834
Yudan WuHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0003-1777-5999
Wenbo ZhangHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0009-0001-8602-2467
Ling WeiHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0009-0004-3869-5546
Huiting CheHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0009-0007-9206-9062
Le XueDepartment of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009 Zhejiang China.ORCID 0000-0002-9627-0763
Yidan GaoHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-7519-7229
Ji TaoHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0003-1129-3147
Shufang QianDepartment of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009 Zhejiang China.ORCID 0000-0002-0212-6331
Wenzhao CaoHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-0991-9529
Jun ZhangDepartment of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, National Center for Neurological Disorders, Fudan University, Shanghai, 200040 China.ORCID 0000-0003-1849-9199
Chengyan WangHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-8890-4973
Mei TianHuman Phenome Institute, Fudan University, 825 Zhangheng Road, Pudong New District, Shanghai, 201203 China.ORCID 0000-0002-1587-2114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human phenomics is defined as the comprehensive collection of observable phenotypes and characteristics influenced by a complex interplay among factors at multiple scales. These factors include genes, epigenetics at the microscopic level, organs, microbiome at the mesoscopic level, and diet and environmental exposures at the macroscopic level. "Phenomic imaging" utilizes various imaging techniques to visualize and measure anatomical structures, biological functions, metabolic processes, and biochemical activities across different scales, both in vivo and ex vivo. Unlike conventional medical imaging focused on disease diagnosis, phenomic imaging captures both normal and abnormal traits, facilitating detailed correlations between macro- and micro-phenotypes. This approach plays a crucial role in deciphering phenomes. This review provides an overview of different phenomic imaging modalities and their applications in human phenomics. Additionally, it explores the associations between phenomic imaging and other omics disciplines, including genomics, transcriptomics, proteomics, immunomics, and metabolomics. By integrating phenomic imaging with other omics data, such as genomics and metabolomics, a comprehensive understanding of biological systems can be achieved. This integration paves the way for the development of new therapeutic approaches and diagnostic tools.

Indexed as

GenomicsImagingImmunomicsMetabolomicsPhenomicsProteomicsTranscriptomics

Identifiers

PMID38223684
PMCPMC10781914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.