Evidence map›Paper›PMID 38223564›Full record

ArticleJournal of materials research2024

Conductive 3D nano-biohybrid systems based on densified carbon nanotube forests and living cells.

Roya Bagheri, Alicia K Ball, Masoud Kasraie, Aparna Chandra, Xinqian Chen, Ibrahim Miskioglu, Zhiying Shan, Parisa Pour Shahid Saeed Abadi

Open access · hybridAbstract read
In one paragraph

Article in Journal of materials research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roya BagheriMechanical Engineering-Engineering Mechanics, Michigan Technological University, Houghton, MI 49931 USA.
Alicia K BallChemical Engineering, Michigan Technological University, Houghton, MI 49931 USA.
Masoud KasraieMaterials Science and Engineering, Michigan Technological University, Houghton, MI 49931 USA.
Aparna ChandraMechanical Engineering-Engineering Mechanics, Michigan Technological University, Houghton, MI 49931 USA.
Xinqian ChenHealth Research Institute, Michigan Technological University, Houghton, MI 49931 USA.
Ibrahim MiskiogluMechanical Engineering-Engineering Mechanics, Michigan Technological University, Houghton, MI 49931 USA.
Zhiying ShanHealth Research Institute, Michigan Technological University, Houghton, MI 49931 USA.
Parisa Pour Shahid Saeed AbadiMechanical Engineering-Engineering Mechanics, Michigan Technological University, Houghton, MI 49931 USA.ORCID 0000-0002-4448-4727
Michigan Technological University · US

Funding

Involvement of the Brain Orexin System in HypertensionR15HL150703 · NHLBI · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI SHAN, ZHIYING · 2020 to 2020
$459k
NHLBI NIH HHS R15 HL150703
6 · The paper itself

Abstract

Conductive biohybrid cell-material systems have applications in bioelectronics and biorobotics. To date, conductive scaffolds are limited to those with low electrical conductivity or 2D sheets. Here, 3D biohybrid conductive systems are developed using fibroblasts or cardiomyocytes integrated with carbon nanotube (CNT) forests that are densified due to interactions with a gelatin coating. CNT forest scaffolds with a height range of 120-240 µm and an average electrical conductivity of 0.6 S/cm are developed and shown to be cytocompatible as evidenced from greater than 89% viability measured by live-dead assay on both cells on day 1. The cells spread on top and along the height of the CNT forest scaffolds. Finally, the scaffolds have no adverse effects on the expression of genes related to cardiomyocyte maturation and functionality, or fibroblast migration, adhesion, and spreading. The results show that the scaffold could be used in applications ranging from organ-on-a-chip systems to muscle actuators. Graphical abstract:

Indexed as

Carbon nanotube forestCardiomyocytesCell scaffoldConductive nano-biohybrid systemsDensificationFibroblastsGelatin

Identifiers

PMID38223564
PMCPMC10784361
OpenAlexW4388266642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.