Evidence map›Paper›PMID 38223505›Full record

ArticleCurrent research in toxicology2024

Evaluation of the diphenyl herbicide, oxyfluorfen, for effects on thyroid hormones in the juvenile rat.

T E Stoker, G D DeVane, A R Buckalew, J R Bailey, J L Ford, A S Murr

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

T E StokerNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. EPA, RTP, NC, United States.
G D DeVaneNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. EPA, RTP, NC, United States.
A R BuckalewNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. EPA, RTP, NC, United States.
J R BaileyNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. EPA, RTP, NC, United States.
J L FordAdvanced Analytical Chemistry Methods Branch, Center for Computational Toxicology & Exposure Chemical Characterization & Exposure Division, CCTE, ORD, U.S. EPA, RTP, NC, United States.
A S MurrNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. EPA, RTP, NC, United States.
Environmental Protection Agency · USOak Ridge Associated Universities · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, oxyfluorfen, a pre- and post-emergent diphenyl ether herbicide, was identified in our laboratory as an inhibitor of iodide uptake by the sodium iodide symporter (NIS), the first key step in the synthesis of thyroid hormones (THs). This inhibition was observed

Indexed as

EndocrineOxyfluorfenSodium iodide symporterThyroid hormones

Identifiers

PMID38223505
PMCPMC10787258
OpenAlexW4390064678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.