Evidence map›Paper›PMID 38223482›Full record

ArticleMediterranean journal of hematology and infectious diseases2024

Effects of Thalidomide on Erythropoiesis and Iron Homeostasis in Transfusion-Dependent β-Thalassemia.

Kun Yang, Xiaodong Liu, Wei Peng, Fang Hua, Lan Li, Kun Chen, Jin Zhang, Shan Luo, Wanting Li, Yuxi Ding and 2 more

Open access · goldAbstract read
In one paragraph

Article in Mediterranean journal of hematology and infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kun Yang *Department of Hematology, Zigong First People's Hospital, Zigong, China.
Xiaodong LiuDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Wei PengDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Fang HuaDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Lan LiDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Kun ChenDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Jin ZhangDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Shan LuoDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Wanting LiDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Yuxi DingDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Jie ChenDepartment of Hematology, Zigong First People's Hospital, Zigong, China.
Jian Xiao *Department of Hematology, Zigong First People's Hospital, Zigong, China.
Zigong First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thalidomide is a therapeutic option for patients with β-thalassemia by increasing fetal hemoglobin and thereby reducing the requirement for blood transfusions. However, information on changes in erythropoiesis and iron homeostasis during thalidomide treatment is lacking. This study investigated the effects of thalidomide treatment on hematologic, erythropoietic, and ironstatus parameters in 22 patients with transfusion-dependent β-thalassemia (TDT). Thalidomide significantly improved anemia endpoints, including increases in hemoglobin (

Indexed as

ErythropoiesisIron homeostasisThalidomideβ-thalassemia

Identifiers

PMID38223482
PMCPMC10786143
OpenAlexW4390489380

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.