Evidence map›Paper›PMID 38223314›Full record

ReviewAmerican journal of blood research2023

A comprehensive review of the ten main platelet receptors involved in platelet activity and cardiovascular disease.

Mehrnoosh Hashemzadeh, Fathima Haseefa, Lee Peyton, Mehrdad Shadmehr, Abdullah M Niyas, Aamir Patel, Ghena Krdi, Mohammad Reza Movahed

Abstract readReview
In one paragraph

Review in American journal of blood research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Genetic Associations ofInternational journal of molecular sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehrnoosh HashemzadehUniversity of Arizona College of Medicine Phoenix, AZ, USA.
Fathima HaseefaUniversity of Arizona College of Medicine Phoenix, AZ, USA.
Lee PeytonPima College Tucson, AZ, USA.
Mehrdad ShadmehrUniversity of Arizona Tucson, AZ, USA.
Abdullah M NiyasUniversity of Arizona College of Medicine Phoenix, AZ, USA.
Aamir PatelUniversity of Arizona College of Medicine Phoenix, AZ, USA.
Ghena KrdiUniversity of Arizona College of Medicine Phoenix, AZ, USA.
Mohammad Reza MovahedUniversity of Arizona College of Medicine Phoenix, AZ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a major cause of death worldwide. Although there are many variables that contribute to the development of this disease, it is predominantly the activity of platelets that provides the mechanisms by which this disease prevails. While there are numerous platelet receptors expressed on the surface of platelets, it is largely the consensus that there are 10 main platelet receptors that contribute to a majority of platelet function. Understanding these key platelet receptors is vitally important for patients suffering from myocardial infarction, CVD, and many other diseases that arise due to overactivation or mutations of these receptors. The goal of this manuscript is to review the main platelet receptors that contribute most to platelet activity.

Indexed as

Cardiovascular diseaseGPIb-IX-VGPIIb/IIIaGPVIP2X1P2Y1P2Y12PAR1PAR4platelet receptorsTXA2α2β1

Identifiers

PMID38223314
PMCPMC10784121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.