Evidence map›Paper›PMID 38223312›Full record

ArticleAmerican journal of blood research2023

Association between Factor-V Leiden and occurrence of acute myocardial infarction using a large NIS database.

Luis Zuniga, Mitchell Davis, Mohammad Reza Movahed, Mehrtash Hashemzadeh, Mehrnoosh Hashemzadeh

Open access · bronzeAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of blood research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luis ZunigaUniversity of Nebraska Medical Center Omaha, NE, USA.
Mitchell DavisDepartment of Dermatology, University of California San Francisco, CA, USA.
Mohammad Reza MovahedCollege of Medicine, University of Arizona Phoenix, AZ, USA.
Mehrtash HashemzadehCollege of Medicine, University of Arizona Phoenix, AZ, USA.
Mehrnoosh HashemzadehCollege of Medicine, University of Arizona Phoenix, AZ, USA.
University of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Factor V Leiden is an inheritable pro-thrombotic genetic condition caused by a point mutation at the 506

backgroundMedical literature regarding the correlation between Factor V Leiden (FVL) and acute myocardial infarctions (AMI) is controversial. We aim to investigate the association between FVL and AMI. MATERIALS AND

methodsUsing the Nationwide Inpatient Sample database, we evaluated any association between Factor V Leiden and acute myocardial infarction in 2016 using ICD-10 codes.

resultsUnivariate analysis (18-40) showed an increase of AMI in patients with FVL 0.6% vs. 0.4%. However, after adjustment for age and comorbid conditions in multivariate analysis, FVL was not significantly associated with acute myocardial infarction (OR 1.44 (95% CI 0.913-2.273,

conclusionIn a population over 18, Factor V Leiden did not correlate with an increased risk of acute myocardial infarction in our studied population.

Indexed as

activated protein C resistancedeep venous thrombosisFactor V LeidenFVLMImyocardial infarctionprimary hypercoagulable state

Identifiers

PMID38223312
PMCPMC10784119
OpenAlexW4390889420

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.