Evidence map›Paper›PMID 38223173›Full record

ArticleBiomedical optics express2024

Effect of chronic kidney disease induced calcification on peripheral vascular perfusion using near-infrared spectroscopic imaging.

Daniela Leizaola, Valentina Dargam, Kevin Leiva, Haniyeh Alirezaei, Joshua Hutcheson, Anuradha Godavarty

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Daniela LeizaolaOptical Imaging Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.ORCID https://orcid.org/0009-0003-8416-7560
Valentina DargamCardiovascular Matrix Remodeling Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.
Kevin LeivaOptical Imaging Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.
Haniyeh AlirezaeiOptical Imaging Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.
Joshua HutchesonCardiovascular Matrix Remodeling Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.
Anuradha GodavartyOptical Imaging Laboratory, Biomedical Engineering Department, 10555 W Flagler St, Miami, FL 33174, USA.ORCID https://orcid.org/0000-0002-6094-5909
Flagler College · USUniversity of Aizu · JP

Funding

Targeting the Caveolae-Dependent Mechanism of Calcifying Extracellular Vesicle FormationR01HL160740 · NHLBI · FLORIDA INTERNATIONAL UNIVERSITY · PI Joshua D Hutcheson · 2022 to 2026
$1.8M
Correlating Aortic Valve Structure to Heart Sound CharacteristicF31HL154671 · NHLBI · FLORIDA INTERNATIONAL UNIVERSITY · PI DARGAM, VALENTINA · 2020 to 2023
$136k
NHLBI NIH HHS F31 HL154671NHLBI NIH HHS R01 HL160740
6 · The paper itself

Abstract

Low-cost techniques that can detect the presence of vascular calcification (VC) in chronic kidney disease (CKD) patients could improve clinical outcomes. In this study, we established a near-infrared spectroscopy-based imaging technique to determine changes in peripheral hemodynamics due to CKD-induced VC. Mice were fed a high-adenine diet with either normal or high levels of phosphate to induce CKD with and without VC, respectively. The mice tail was imaged to evaluate hemodynamic changes in response to occlusion. The rate of change in oxyhemoglobin in response to occlusion showed a statistically significant difference in the presence of VC in the mice.

Identifiers

PMID38223173
PMCPMC10783904
OpenAlexW4389057867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.