Evidence map›Paper›PMID 38223171›Full record

ArticleBiomedical optics express2024

High resolution terahertz ATR frequency-domain spectroscopy for monitoring spinal cord injury in rats.

Xing Fang, Hanxu Huang, Hongqi Zhang, Zuomin Yang, Zhidong Lyu, Hang Yang, Nan Li, Tengfei Zhao, Xianbin Yu, Lu Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Xing FangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Hanxu HuangDepartment of Orthopedic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Hongqi ZhangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Zuomin YangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Zhidong LyuCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Hang YangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Nan LiCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Tengfei ZhaoDepartment of Orthopedic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Xianbin YuCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.ORCID https://orcid.org/0000-0003-0063-4460
Lu ZhangCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.ORCID https://orcid.org/0000-0001-9567-155X
Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNKongju National University · KRXING Technologies (Australia) · AUZhuhai Institute of Advanced Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic spinal cord injury (SCI) can lead to permanent neurological impairment, underscoring the urgency of regular therapeutic intervention and monitoring. In this study, we propose a new strategy for monitoring spinal cord injury through serum based on high-resolution THz attenuated total reflection frequency domain spectroscopy (THz-ATR-FDS). We demonstrated serum spectral differences at different time points after experimental SCI in rats. We also studied the relationship between serum lipid concentration and the time of SCI, which revealed the potential of lipid molecules as biomarkers of SCI. In addition, based on the principal component analysis (PCA) and least squares regression (LSR) models, the quantitative relationship between the refractive index spectrum and lipid concentration in serum was automatically analyzed. This work highlights terahertz spectroscopy as a promising tool for label-free, periodic, and efficient monitoring of SCI.

Identifiers

PMID38223171
PMCPMC10783913
OpenAlexW4389948928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.