Evidence map›Paper›PMID 38223036›Full record

ArticleQuantitative imaging in medicine and surgery2024

Pericoronary adipose tissue attenuation in patients with acute aortic dissection based on coronary computed tomography angiography.

Yong-Bo Tu, Min Gu, Shao-Quan Zhou, Gang Xie, Li-Li Liu, Feng-Bin Deng, Kang Li

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Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yong-Bo TuDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Min GuDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Shao-Quan ZhouDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Gang XieDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Li-Li LiuDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Feng-Bin DengDepartment of Radiology, Chongqing General Hospital, Chongqing, China.
Kang LiDepartment of Radiology, Chongqing General Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periaortic fat is associated with coronary disease. Thus, it was hypothesized that the inflammation associated with acute aortic dissection (AAD) spreads to pericoronary adipose tissue (PCAT) via thoracic periaortic fat. Pericoronary adipose tissue attenuation (PCATa) serves as a marker for inflammation of perivascular adipose tissue (PVAT). This study sought to examine PCATa in individuals diagnosed with AAD. Methods: Consecutive patients with chest pain from May 2020 to September 2022 were prospectively enrolled in this study and underwent coronary computed tomography angiography (CCTA) and/or aorta computed tomography angiography (CTA). Based on the results of the CTA, the patients were divided into the following two groups: (I) the AAD group; and (II) the non-AAD group. PCATa of the right coronary angiography (RCA), left anterior descending (LAD), and left circumflex (LCx) was quantified for each patient using semi-automated software. The PCATa values were compared between the AAD and non-AAD patients according to the atherosclerosis of the coronary arteries. Similarly, the PCATa values of the AAD patients were compared between the preoperative and postoperative steady states. Results: A total of 136 patients (42 female, 94 male; mean age: 63.3±11.9 years) were divided into the two groups according to the presence of aortic dissection on CTA. The RCA Conclusions: PCATa on computed tomography was increased in patients with AAD regardless of the presence or absence of coronary artery disease (CAD). This suggests that vascular inflammation is present in AAD independent of CAD. Further research should be conducted to investigate the potential of this imaging biomarker to predict AAD and monitor patients' responses to therapies for AAD.

Indexed as

Acute aortic dissection (AAD)coronary computed tomography angiography (CCTA)pericoronary adipose tissue (PCAT)

Identifiers

PMID38223036
PMCPMC10784082

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.