ArticleQuantitative imaging in medicine and surgery2024
Feasibility of using 8 mL of iodinated contrast media in cerebral computed tomographic angiography with a dual-layer spectral detector.
Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Feasibility of reducing the contrast dose in infants and children with complex congenital heart disease using virtual monoenergetic images on dual-layer spectral detector computed tomography.Pediatric radiology · 2026Trial
- Impact of arm position on low dose dual-source CT one-step aortic and cerebral-carotid artery angiography image quality and radiation dose.BMC medical imaging · 2025Trial
- Efficiency and Optimization of Iodinated Contrast Agents in Cerebral Aneurysm CT Angiography: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Feasibility of Ultra-Dilute Iodine Contrast Agent in Dual-Layer Spectral CT for Pulmonary Artery ImagingCurrent medical imaging · 2026Article
- Correlation between perfusion and dual-layer spectral-detector CT in patients with cerebrovascular disorders.European radiology · 2025Article
- Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses.European journal of radiology open · 2025Article
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7 authors.
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Abstract
Background: Virtual monoenergetic images (VMIs) at a low energy level can improve image quality when the amount of iodinated contrast media (CM) is reduced. The purpose was to evaluate the feasibility of using an extremely low CM volume and injection rate in cerebral computed tomography angiography (CTA) on a dual-layer spectral detector computed tomography (CT). Methods: Patients who were clinically suspected of intracranial aneurysm or cerebrovascular diseases were included in our study (from June to November 2022). In this prospective study, 80 patients were randomly enrolled into group A (8 mL of CM with a 1-mL/s flow rate) or group B (40 mL of CM with 4-mL/s flow rate). The VMIs at 40-70 keV in group A and polychromatic conventional images in the 2 groups were reconstructed. CT attenuation, image noise, contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR) were evaluated via the Results: In group A, the subjective image quality score, CT attenuation, and CNR of the internal carotid artery (ICA) and middle cerebral artery (MCA) were the highest on VMIs at 40 keV. The image noise on VMIs at 40 keV was 5.08±0.84 Hounsfield units. The subjective image quality score, CT value of the ICA, MCA, and cerebral parenchyma on VMIs at 40 keV in group A were similar to those in group B (all P values >0.05). Compared to those in group B, the VMIs at 40 keV in group A demonstrated a significantly higher mean SNR and CNR of the ICA (mean SNR: 46.22±20.18 Conclusions: Cerebral CTA on VMIs at 40 keV with 8 mL of CM and a 1-mL/s injection rate can provide diagnostic image quality.
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