Evidence map›Paper›PMID 38222924›Full record

ArticleCase reports in clinical pathology2015

Refractory anaplastic astrocytoma responsive to PCV in combination with bevacizumab.

Arun Swaminathan, Donita D Lightner, Thomas Pittman, Craig Horbinski, John Lee Villano

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in clinical pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arun SwaminathanDepartment of Neurology, University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States.
Donita D LightnerDepartment of Neurology, University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States.
Thomas PittmanDepartment of Neurosurgery, University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States.
Craig HorbinskiDepartment of Pathology, University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States.
John Lee VillanoDepartment of Neurology, University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States.
Albert B. Chandler Hospital · USUniversity of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

We present a patient with anaplastic astrocytoma who had recurrent disease after treatment with surgery, radiation, procarbazine, lomustine (CCNU) and vincristine (PCV) over one year followed by poor response to second line treatment with temozolomide, irinotecan with bevacizumab, Novocure TTF therapy successively over a four year period after her initial treatment who then responded to PCV in combination with bevacizumab as third line therapy. This is the first report demonstrating benefit of concurrent PCV and bevacizumab treatment in a highly treatment refractory tumor.

Indexed as

Anaplastic astrocytomaBrain tumorRecurrent tumorTumor treatment

Identifiers

PMID38222924
PMCPMC10786628
OpenAlexW2118286623

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.