Evidence map›Paper›PMID 38222433›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2023

Backdoor Adjustment of Confounding by Provenance for Robust Text Classification of Multi-institutional Clinical Notes.

Xiruo Ding, Zhecheng Sheng, Meliha Yetişgen, Serguei Pakhomov, Trevor Cohen

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiruo DingUniversity of Washington, Seattle, WA, USA.
Zhecheng ShengUniversity of Minnesota, Twin Cities, MN, USA.
Meliha YetişgenUniversity of Washington, Seattle, WA, USA.
Serguei PakhomovUniversity of Minnesota, Twin Cities, MN, USA.
Trevor CohenUniversity of Washington, Seattle, WA, USA.

Funding

DeconDTN: Deconfounding Deep Transformer Networks for Clinical NLPR01LM014056 · NLM · UNIVERSITY OF WASHINGTON · PI COHEN, TREVOR, PAKHOMOV, SERGUEI VS · 2022 to 2025
$1.7M
NLM NIH HHS R01 LM014056
6 · The paper itself

Abstract

Natural Language Processing (NLP) methods have been broadly applied to clinical tasks. Machine learning and deep learning approaches have been used to improve the performance of clinical NLP. However, these approaches require sufficiently large datasets for training, and trained models have been shown to transfer poorly across sites. These issues have led to the promotion of data collection and integration across different institutions for accurate and portable models. However, this can introduce a form of bias called confounding by provenance. When source-specific data distributions differ at deployment, this may harm model performance. To address this issue, we evaluate the utility of backdoor adjustment for text classification in a multi-site dataset of clinical notes annotated for mentions of substance abuse. Using an evaluation framework devised to measure robustness to distributional shifts, we assess the utility of backdoor adjustment. Our results indicate that backdoor adjustment can effectively mitigate for confounding shift.

Indexed as

Electronic Health RecordsSubstance-Related DisordersData CollectionHumansMachine LearningMulticenter Studies as TopicNatural Language Processing

Identifiers

PMID38222433
PMCPMC10785933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.