Evidence map›Paper›PMID 38222413›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2023

An Automated Strategy to Calculate Medication Regimen Complexity.

Yuzhi Lu, Ariel R Green, Rosalphie Quiles, Casey Overby Taylor

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuzhi LuJohns Hopkins University Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, MD.
Ariel R GreenJohns Hopkins University School of Medicine, Division of Geriatric Medicine and Gerontology, Baltimore, MD.
Rosalphie QuilesJohns Hopkins University School of Medicine, Division of Geriatric Medicine and Gerontology, Baltimore, MD.
Casey Overby TaylorJohns Hopkins University Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, MD.

Funding

eAlign: A Patient Portal-based Intervention to Align Medications with What Matters MostR01AG077011 · NIA · JOHNS HOPKINS UNIVERSITY · PI Ariel Green, CHRISTINE D JONES · 2022 to 2026
$3.9M
Bladder Antimuscarinics in Dementia: A Model of Decisions About Potentially Inappropriate MedicinesK23AG054742 · NIA · JOHNS HOPKINS UNIVERSITY · PI GREEN, ARIEL · 2017 to 2020
$795k
NIA NIH HHS K23 AG054742NIA NIH HHS R01 AG077011
6 · The paper itself

Abstract

Understanding medication regimen complexity is important to understand what patients may benefit from pharmacist interventions. Medication Regimen Complexity Index (MRCI), a 65-item tool to quantify the complexity by incorporating the count, dosage form, frequency, and additional administration instructions of prescription medicines, provides a more nuanced way of assessing complexity. The goal of this study was to construct and validate a computational strategy to automate the calculation of MRCI. The performance of our strategy was evaluated by comparing our calculated MRCI values with gold-standard values, using correlation coefficients and population distributions. The results revealed satisfactory performance to calculate the sub-score of MRCI that includes dosage form and frequency (76 to 80% match with gold standard), and fair performance for sub-score related to additional direction (52% match with gold standard). Our automated strategy shows potential to help reduce the effort for manually calculating MRCI and highlights areas for future development efforts.

Indexed as

Prescription DrugsHumansMedication AdherencePharmacistsPolypharmacyPrescription Drugs

Identifiers

PMID38222413
PMCPMC10785893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.