Evidence map›Paper›PMID 38222349›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2023

Predicting premature discontinuation of medication for opioid use disorder from electronic medical records.

Ivan Lopez, Sajjad Fouladvand, Scott Kollins, Chwen-Yuen Angie Chen, Jeremiah Bertz, Tina Hernandez-Boussard, Anna Lembke, Keith Humphreys, Adam S Miner, Jonathan H Chen

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ivan LopezDepartment of Medicine, Biomedical Informatics Research, Stanford Medicine, Stanford University, CA.
Sajjad FouladvandDepartment of Medicine, Biomedical Informatics Research, Stanford Medicine, Stanford University, CA.
Scott KollinsHolmusk, NY.
Chwen-Yuen Angie ChenPrimary Care and Population Health, Stanford Medicine, Stanford University, CA.
Jeremiah BertzCenter for the Clinical Trials Network, National Institute on Drug Abuse, MD.
Tina Hernandez-BoussardDepartment of Medicine, Biomedical Informatics Research, Stanford Medicine, Stanford University, CA.
Anna LembkeDepartment of Psychiatry and Behavioral Sciences, Stanford Medicine, Stanford University, CA.
Keith HumphreysDepartment of Psychiatry and Behavioral Sciences, Stanford Medicine, Stanford University, CA.
Adam S MinerDepartment of Psychiatry and Behavioral Sciences, Stanford Medicine, Stanford University, CA.
Jonathan H ChenDepartment of Medicine, Biomedical Informatics Research, Stanford Medicine, Stanford University, CA.

Funding

Measuring and Predicting Appropriate Antibiotic Use to Combat Resistant BacteriaR01AI178121 · NIAID · STANFORD UNIVERSITY · PI JONATHAN H. CHEN · 2023 to 2026
$3.1M
NIAID NIH HHS R01 AI178121
6 · The paper itself

Abstract

Medications such as buprenorphine-naloxone are among the most effective treatments for opioid use disorder, but limited retention in treatment limits long-term outcomes. In this study, we assess the feasibility of a machine learning model to predict retention vs. attrition in medication for opioid use disorder (MOUD) treatment using electronic medical record data including concepts extracted from clinical notes. A logistic regression classifier was trained on 374 MOUD treatments with 68% resulting in potential attrition. On a held-out test set of 157 events, the full model achieved an area under the receiver operating characteristic curve (AUROC) of 0.77 (95% CI: 0.64-0.90) and AUROC of 0.74 (95% CI: 0.62-0.87) with a limited model using only structured EMR data. Risk prediction for opioid MOUD retention vs. attrition is feasible given electronic medical record data, even without necessarily incorporating concepts extracted from clinical notes.

Indexed as

Electronic Health RecordsOpioid-Related DisordersAnalgesics, OpioidArea Under CurveHumansMachine LearningROC CurveAnalgesics, Opioid

Identifiers

PMID38222349
PMCPMC10785878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.