Evidence map›Paper›PMID 38222057›Full record

ArticleNeuro-oncology practice2024

Optimizing an exercise training program in pediatric brain tumour survivors: Does timing postradiotherapy matter?

Éloïse Baudou, Jennifer L Ryan, Elizabeth Cox, Lisa Nham, Krista Johnston, Éric Bouffet, Ute Bartels, Brian Timmons, Cynthia de Medeiros, Donald J Mabbott

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01944761 (The Neuro-protective Effects of Exercise in Children Treated With Cranial Radiation for Brain Tumors), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01944761 nacompletednot on this map

The Neuro-protective Effects of Exercise in Children Treated With Cranial Radiation for Brain Tumors

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2011 to 2015Enrolled32ConditionsBrain TumorArmsExercise Program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Éloïse BaudouNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-3659-5766
Jennifer L RyanNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Elizabeth CoxNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lisa NhamNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Krista JohnstonDivisions of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Éric BouffetDivisions of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ute BartelsDivisions of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-2112-5251
Brian TimmonsDepartment of Pediatrics, Child Health and Exercise Medicine Program, McMaster University, Hamilton, ON, Canada.
Cynthia de MedeirosNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Donald J MabbottNeurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Hospital for Sick Children · CAMcMaster University · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While exercise training (ET) programs show positive outcomes in cognition, motor function, and physical fitness in pediatric brain tumor (PBT) survivors, little is known about the optimal timing of intervention. The aim of this work was to explore the feasibility and benefits of ET based on its timing after radiotherapy. Methods: This retrospective analysis (ClinicalTrials.gov, NCT01944761) analyzed data based on the timing of PBT survivors' participation in an ET program relative to their completion of radiotherapy: <2 years ( Results: Two to five years postradiotherapy was the optimal time period in terms of adherence (88.5%), retention (100%), and satisfaction (more fun, more enjoyable and recommend it more to other children). However, the benefits of ET program on memory recognition ( Conclusion: Participation in an ET program should be offered as part of routine postradiotherapy care in the first 1-2 years and strongly encouraged in the first 5 years.

Indexed as

brain recoverycranial radiationexerciseneuroplasticitypediatric brain tumor

Identifiers

PMID38222057
PMCPMC10785595
OpenAlexW4386573652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.