Evidence map›Paper›PMID 38222037›Full record

ArticleChemistry of materials : a publication of the American Chemical Society2023

MOFganic Chemistry: Challenges and Opportunities for Metal-Organic Frameworks in Synthetic Organic Chemistry.

Bayu I Z Ahmad, Kaitlyn T Keasler, Emily E Stacy, Sijing Meng, Thomas J Hicks, Phillip J Milner

Open access · greenAbstract read
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Caging the Chlorine Radical: Chemoselective Photocatalytic C(spJournal of the American Chemical Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Cooperative Photoredox Catalysis Under Confinement.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  7. Article
  8. Review
  9. Gas Delivery Relevant to Human Health using Porous Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  10. Article
  11. Simplifying the Synthesis of Metal-Organic Frameworks.Accounts of materials research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bayu I Z AhmadDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Kaitlyn T KeaslerDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Emily E StacyDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Sijing MengDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Thomas J HicksDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Phillip J MilnerDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853, United States.
Cornell University · US

Funding

Taming Fluorine: Metal-Organic Frameworks for the Heterogeneous Delivery of Fluorinated Building BlocksR35GM138165 · NIGMS · CORNELL UNIVERSITY · PI Phillip John Milner · 2020 to 2026
$2.9M
NIGMS NIH HHS R35 GM138165
6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) are porous, crystalline solids constructed from organic linkers and inorganic nodes that have been widely studied for applications in gas storage, chemical separations, and drug delivery. Owing to their highly modular structures and tunable pore environments, we propose that MOFs have significant untapped potential as catalysts and reagents relevant to the synthesis of next-generation therapeutics. Herein, we outline the properties of MOFs that make them promising for applications in synthetic organic chemistry, including new reactivity and selectivity, enhanced robustness, and user-friendly preparation. In addition, we outline the challenges facing the field and propose new directions to maximize the utility of MOFs for drug synthesis. This perspective aims to bring together the organic and MOF communities to develop new heterogeneous platforms capable of achieving synthetic transformations that cannot be replicated by homogeneous systems.

Identifiers

PMID38222037
PMCPMC10785605
OpenAlexW4381741243

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.