ArticleWorld journal of gastrointestinal surgery2023
Effects of remifentanil combined with propofol on hemodynamics and oxidative stress in patients undergoing resection of rectal carcinoma.
Article in World journal of gastrointestinal surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Effects of different doses of remifentanil combined with sevoflurane anesthesia on postoperative analgesia and hemodynamics in pediatric patients undergoing laparoscopic inguinal hernia repair.BMC anesthesiology · 2025Trial
- Perioperative endocrine dynamics in euthyroid versus hyperthyroid patients with Graves' disease undergoing total thyroidectomy: a prospective cohort study.BMC surgery · 2026Article
- Remifentanil-Propofol versus Propofol Alone in Patients with Severe Traumatic Brain Injury: A Retrospective Cohort Study on Anesthesia Outcomes.Drug design, development and therapy · 2025Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundRectal carcinoma (RC) treatment primarily involves laparoscopic surgery, which may induce significant hemodynamic changes and weaken immune function. Certain anesthetic approaches using opioid drugs (including remifentanil and sufentanil) pose risks, such as hypotension.
aimTo determine the effects of remifentanil combined with propofol on hemodynamics and oxidative stress in patients undergoing RC resection.
methodsA total of 211 patients one hundred and four patients with RC treated at the First Affiliated Hospital of Dalian Medical University between November 2018 and November 2022 were retrospectively analyzed. Among them, the remifentanil group included 45 patients receiving remifentanil with propofol anesthesia and the sufentanil group included 59 patients receiving sufentanil with propofol anesthesia. Changes in the hemodynamic index, oxidative stress index, general data, consumption of remifentanil, and use of vasoactive drugs were compared. The incidences of adverse reactions were calculated.
resultsThe two groups did not significantly differ in terms of operation, anesthesia, and extubation times (
conclusionRemifentanil combined with propofol can improve hemodynamics and relieve oxidative stress in patients undergoing RC resection.
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