ArticleOpen forum infectious diseases2024
Effect of Antibiotic Administration Before Joint Aspiration on Synovial Fluid White Blood Cell Count in Native Joint Septic Arthritis.
Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Efficacy and limitations of a web-based native adult knee septic arthritis calculator in urban trauma care.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Graphical Representation of Cell Count in Native Joint Aspirates.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Therapeutic Strategies and Clinical Outcomes of Infections Following Anterior Cruciate Ligament Reconstruction: A Narrative Review.Orthopaedic surgery · 2026Review
- Article
- Septic arthritis and prosthetic joint infections: microbial spectrum and evolving resistance patterns.Journal of bone and joint infection · 2026Article
- Synovial Fluid Analysis in Melioidosis: Experiences from the Darwin Prospective Melioidosis Study.Pathogens (Basel, Switzerland) · 2025Article
- Article
- Rapid access microscopy and real-time case discussion via a secure messaging app improves diagnostic accuracy and management of acute hot swollen joints.BMJ open quality · 2025Article
- Sensitivity and Specificity of Natural Language Processing Systems for Identification of Hospitalized People Who Use Drugs.Open forum infectious diseases · 2025Article
- Effect of Antibiotic Therapy Before Arthrocentesis on Synovial Fluid Cell Count and Differential for Diagnosis of Native Joint Septic Arthritis.Open forum infectious diseases · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study was performed to assess the impact of preaspiration antibiotics on synovial fluid analysis and timing of operative treatment in native-joint septic arthritis. Methods: We performed a retrospective record review of adult patients from an urban level 1 trauma center with native joint septic arthritis in 2015-2019, identified by means of codes from the Results: Of the 126 patients with septic joints included, nearly two-thirds (n = 80 [63.5%]) received antibiotics before joint aspiration. The synovial fluid WBC count, percentage of PMNs, and rate of culture positivity were significantly lower in patients who received preaspiration antibiotics than in those who did not (mean WBC count, 51 379.1/μL [standard deviation, 52 576.3/μL] vs 92 162.7/μL [59 330.6/μL], respectively [ Conclusions: The administration of antibiotics before joint aspiration for suspected septic arthritis appears to decrease the synovial fluid WBC count, the percentage of PMNs, and the rate of culture positivity. Efforts to limit antibiotic administration before joint aspiration are important to minimize diagnostic dilemmas and circumvent treatment delays.
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