Evidence map›Paper›PMID 38221824›Full record

ArticleESC heart failure2024

Giant cell myocarditis with prolonged cardiac standstill after drug-induced hypersensitivity syndrome: a case report.

Ryohei Ono, Hiroki Kohno, Sae Kaminota, Kaoruko Aoki, Hirotoshi Kato, Togo Iwahana, Takanori Aihara, Masayuki Ota, Goro Matsumiya, Yoshio Kobayashi

Open access · goldAbstract readCase Reports
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ryohei OnoDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID https://orcid.org/0000-0002-4875-7470
Hiroki KohnoDepartment of Cardiovascular Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Sae KaminotaChiba University School of Medicine, Chiba, Japan.
Kaoruko AokiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Hirotoshi KatoDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Togo IwahanaDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Takanori AiharaDepartment of Pathology, Chiba University Hospital, Chiba, Japan.
Masayuki OtaDepartment of Diagnostic Pathology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Goro MatsumiyaDepartment of Cardiovascular Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Yoshio KobayashiDepartment of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Chiba University · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell myocarditis (GCM) is a rare but fatal disease that can lead to cardiac failure. Survival with a cardiac standstill requires mechanical circulatory support or a biventricular assist device (BiVAD) and prolonged survival is extremely rare. Drug-induced hypersensitivity syndrome (DIHS) is a severe cutaneous adverse reaction. Some cases of DIHS are reportedly associated with the onset of GCM. We present a case of a 28-year-old woman who developed GCM during steroid tapering after DIHS. She went into continuous cardiac standstill but survived for 74 days under BiVAD support. Our case is noteworthy because the histopathologic specimens obtained on three occasions contributed to the diagnosis of this particular condition over time. We also reviewed previous literature on concomitant cases of GCM and DIHS. We found that two are potentially associated and most cases of GCM occur within 3 months of DIHS during steroid tapering.

Indexed as

Heart FailureMyocarditisAdultFemaleGiant CellsHumansSteroidsSteroidsBiventricular assist deviceCardiac arrestCardiac standstillDrug‐induced hypersensitivity syndromeGiant cell myocarditisReview

Identifiers

PMID38221824
PMCPMC10966221
OpenAlexW4390883300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.