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ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2024

Bayesian discrete lognormal regression model for genomic prediction.

Abelardo Montesinos-López, Humberto Gutiérrez-Pulido, Sofía Ramos-Pulido, José Cricelio Montesinos-López, Osval A Montesinos-López, José Crossa

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Abelardo Montesinos-LópezDepartamento de Matemáticas, Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, C. P. 44430, Guadalajara, Jalisco, México.
Humberto Gutiérrez-PulidoDepartamento de Matemáticas, Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, C. P. 44430, Guadalajara, Jalisco, México.
Sofía Ramos-PulidoDepartamento de Matemáticas, Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, C. P. 44430, Guadalajara, Jalisco, México.
José Cricelio Montesinos-LópezDepartment of Public Health Sciences, University of California Davis, Davis, CA, 95616, USA.
Osval A Montesinos-LópezFacultad de Telemática, Universidad de Colima, C. P. 28040, Colima, Edo. de Colima, México. osval78t@gmail.com.ORCID http://orcid.org/0000-0002-3973-6547
José CrossaInternational Maize and Wheat Improvement Center (CIMMYT), Carretera México-Veracruz Km. 45, El Batán, C. P. 56237, Texcoco, Edo. de México, México. jcrossa@cgiar.org.ORCID http://orcid.org/0000-0001-9429-5855

Funding

Bill & Melinda Gates Foundation INV-003439
6 · The paper itself

Abstract

key messageGenomic prediction models for quantitative traits assume continuous and normally distributed phenotypes. In this research, we proposed a novel Bayesian discrete lognormal regression model. Genomic selection is a powerful tool in modern breeding programs that uses genomic information to predict the performance of individuals and select those with desirable traits. It has revolutionized animal and plant breeding, as it allows breeders to identify the best candidates without labor-intensive and time-consuming phenotypic evaluations. While several statistical models have been developed, most of them have been for quantitative continuous traits and only a few for count responses. In this paper, we propose a discrete lognormal regression model in the Bayesian context, that with a Gibbs sampler to explore the corresponding posterior distribution and make the predictions. Two datasets of resistance disease is used in the wheat crop and are then evaluated against the traditional Gaussian model and a lognormal model. The results indicate the proposed model is a competitive and natural model for predicting count genomic traits.

Indexed as

Models, GeneticPlant BreedingAnimalsBayes TheoremGenomeGenomicsHumansPhenotype

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.