Evidence map›Paper›PMID 38220222›Full record

Trial reportThe British journal of nutrition2024

Ingestion of a variety of non-animal-derived dietary protein sources results in diverse postprandial plasma amino acid responses which differ between young and older adults.

Ino van der Heijden, Sam West, Alistair J Monteyne, Tim J A Finnigan, Doaa R Abdelrahman, Andrew J Murton, Francis B Stephens, Benjamin T Wall

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The British journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Ingestion of 'whole cell' or 'split cell'Frontiers in nutrition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ino van der HeijdenDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, Heavitree Road, University of Exeter, ExeterEX1 2LU, UK.ORCID 0000-0001-5248-499X
Sam WestDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, Heavitree Road, University of Exeter, ExeterEX1 2LU, UK.ORCID 0000-0002-5432-863X
Alistair J MonteyneDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, Heavitree Road, University of Exeter, ExeterEX1 2LU, UK.
Tim J A FinniganNew Era Foods, Hutton Rudby, Yarm, UK.
Doaa R AbdelrahmanDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Andrew J MurtonDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0002-9474-9113
Francis B StephensDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, Heavitree Road, University of Exeter, ExeterEX1 2LU, UK.
Benjamin T WallDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, Heavitree Road, University of Exeter, ExeterEX1 2LU, UK.ORCID 0000-0002-6019-6709
University of Exeter · GBThe University of Texas Medical Branch at Galveston · US

Funding

UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
NIA NIH HHS P30 AG024832
6 · The paper itself

Abstract

Whole-body tissue protein turnover is regulated, in part, by the postprandial rise in plasma amino acid concentrations, although minimal data exist on the amino acid response following non-animal-derived protein consumption. We hypothesised that the ingestion of novel plant- and algae-derived dietary protein sources would elicit divergent plasma amino acid responses when compared with vegan- and animal-derived control proteins. Twelve healthy young (male (m)/female (f): 6/6; age: 22 ± 1 years) and 10 healthy older (m/f: 5/5; age: 69 ± 2 years) adults participated in a randomised, double-blind, cross-over trial. During each visit, volunteers consumed 30 g of protein from milk, mycoprotein, pea, lupin, spirulina or chlorella. Repeated arterialised venous blood samples were collected at baseline and over a 5-h postprandial period to assess circulating amino acid, glucose and insulin concentrations. Protein ingestion increased plasma total and essential amino acid concentrations (

Indexed as

Amino AcidsCross-Over StudiesDietary ProteinsInsulinPostprandial PeriodSpirulinaAdultAgedAge FactorsAmino Acids, EssentialAnimalsBlood GlucoseChlorellaDouble-Blind MethodFemaleHumansAmino AcidsAmino Acids, EssentialBlood GlucoseDietary ProteinsInsulinMilk ProteinsPea ProteinsPlant Proteins, DietaryAgeingAlgaeAmino acidsBioavailabilityMycoproteinPlant protein

Identifiers

PMID38220222
PMCPMC11043913
OpenAlexW4390863568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.