Evidence map›Paper›PMID 38219726›Full record

ArticleUrologia internationalis2024

Associations between Urinary Concentrations of Polycyclic Aromatic Hydrocarbons and Overactive Bladder in US Adults: Data from the National Health and Nutrition Examination Survey 2005-2016.

Shihang Pu, Qi Li, Zhijun Tao, Songbo Wang, Xiangyu Meng, Shangqian Wang, Zengjun Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urologia internationalis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shihang PuDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qi LiDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhijun TaoDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Songbo WangDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiangyu MengDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Shangqian WangDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zengjun WangDepartment of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolycyclic aromatic hydrocarbons (PAHs) are a group of chemicals that can induce oxidative stress and related cytotoxicity. Whether urinary concentrations of PAHs have effects on overactive bladder (OAB) in the general population is still unclear. This study investigated the associations between urinary PAHs and OAB.

methods7,146 adults aged over 20 who participated in the US National Health and Nutrition Examination Survey 2005-2016 were studied. The impact of the six PAHs on OAB was evaluated by multivariate logistic regression, and percent changes related to different quartiles of those six PAH levels were calculated. Confounders including age, logarithmic urinary creatinine, gender, race, body mass index, educational level, marriage, poverty income ratio, diabetes, hypertension, and metabolic syndrome were controlled.

resultsThere is a significant positive correlation between urinary concentrations of the six PAHs we include in the study and the occurrence of OAB. Furthermore, individuals with higher PAH levels also reported a more severe OAB symptom score (OABSS).

conclusionsOur findings revealed that adult men in the USA with higher urinary PAHs had a higher risk of OAB incidence. These findings suggest the importance of strong environmental regulation of PAHs to protect population health. However, the underlying mechanisms still need further exploration.

Indexed as

Diabetes MellitusMetabolic SyndromePolycyclic Aromatic HydrocarbonsUrinary Bladder, OveractiveAdultBiomarkersHumansMaleNutrition SurveysBiomarkersPolycyclic Aromatic HydrocarbonsNHANESOveractive bladderPolycyclic aromatic hydrocarbonsReproduction toxicity

Identifiers

PMID38219726
PMCPMC10994579
OpenAlexW4390813395

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.