ArticleInternational journal of computer assisted radiology and surgery2024
Artificial intelligence-based image-domain material decomposition in single-energy computed tomography for head and neck cancer.
Article in International journal of computer assisted radiology and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- The Role of Low-Energy Virtual Monoenergetic Images Derived From Dual-Energy Computed Tomography in Tumor Segmentation for Head and Neck Radiation Therapy: A Contouring Study.Advances in radiation oncology · 2026Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWhile dual-energy computed tomography (DECT) images provide clinically useful information than single-energy CT (SECT), SECT remains the most widely used CT system globally, and only a few institutions can use DECT. This study aimed to establish an artificial intelligence (AI)-based image-domain material decomposition technique using multiple keV-output learning of virtual monochromatic images (VMIs) to create DECT-equivalent images from SECT images.
methodsThis study involved 82 patients with head and neck cancer. Of these, the AI model was built with data from the 67 patients with only DECT scans, while 15 patients with both SECT and DECT scans were used for SECT testing. Our AI model generated VMI
resultsThe prediction time was 5.4 s per patient. The proposed method with the MDI loss function quantitatively provided more accurate DECT-equivalent images than the model trained with the loss for VMIs only. Using real 120-kVp SECT images, the trained model produced precise DECT images of excellent quality.
conclusionIn this study, we developed an AI-based material decomposition approach for head and neck cancer patients by introducing the loss function for MDIs via multiple keV-output learning. Our results suggest the feasibility of AI-based image-domain material decomposition in a conventional SECT system without a DECT scanner.
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Registered trials
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