Evidence map›Paper›PMID 38218976›Full record

ArticleCommunications biology2024

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy.

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Weihui Yan *Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shanshan Chen *Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ying WangDivision of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yaying YouDivision of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ying LuShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Weipeng WangDepartment of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Bo WuDivision of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jun DuShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Shicheng PengShanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China.
Wei CaiDivision of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. caiw204@sjtu.edu.cn.ORCID 0000-0002-4355-5693
Yongtao XiaoDivision of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. xiaoyongtao@xinhuamed.com.cn.ORCID 0000-0002-0964-609X
Shanghai Jiao Tong University · CNShanghai Institute of Nutrition and Health · CNShanghai University · CN

Funding

Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 22ZR1480600
6 · The paper itself

Abstract

A recent single-cell survey of the small-intestinal epithelium suggests that mucosal pentraxin 2 (Mptx2) is a new Paneth cell marker, but its function and involved mechanism in the Paneth cell are still unknown. Therefore, we create Mptx2 knockout (Mptx2

Indexed as

LipopolysaccharidesMethicillin-Resistant Staphylococcus aureusAnimalsAutophagyHomeostasisInflammationIntestinesMiceLipopolysaccharides

Identifiers

PMID38218976
PMCPMC10787791
OpenAlexW4390839198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.