Evidence map›Paper›PMID 38218954›Full record

ArticleScientific reports2024

Associations between low serum levels of ANRIL and some common gene SNPs in Iranian patients with premature coronary artery disease.

Elham Taheri Bajgan, Ali Zahedmehr, Farshad Shakerian, Majid Maleki, Hooman Bakhshandeh, Seyed Javad Mowla, Mahshid Malakootian

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. ANRIL: A Long Noncoding RNA in Age-related Diseases.Mini reviews in medicinal chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elham Taheri BajganMolecular Genetics Department, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Ali ZahedmehrCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Farshad ShakerianCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Majid MalekiCardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Hooman BakhshandehCardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seyed Javad MowlaMolecular Genetics Department, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran. sjmowla@yahoo.com.
Mahshid MalakootianCardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran. malakootian@rhc.ac.ir.
Shaheed Rajaei Cardiovascular Medical and Research Center · IRIran University of Medical Sciences · IRTarbiat Modares University · IR

Funding

National Institute for Medical Research Development 943104Research Deputyship of Rajaie Cardiovascular Medical and Research Center 96060
6 · The paper itself

Abstract

Coronary artery disease (CAD) is the major cause of mortality in the world. Premature development of CAD can be attributed to women under 55 and men under 45. Many genetic factors play a part in premature CAD. Among them, ANRIL, a long noncoding RNA is located at the 9p21 risk locus, and its expression seems to be correlated with CAD. In the current study, premature CAD and control blood samples, with and without Type 2 Diabetes (T2D), were genotyped for six SNPs at the 9p21 locus. Additionally, ANRIL serum expression was assessed in both groups using real-time PCR. It was performed using different primers targeting exons 1, 5-6, and 19. The χ

Indexed as

Coronary Artery DiseaseDiabetes Mellitus, Type 2RNA, Long NoncodingFemaleGenetic Predisposition to DiseaseHumansIranMalePolymorphism, Single NucleotideCDKN2B antisense RNA, humanRNA, Long Noncoding

Identifiers

PMID38218954
PMCPMC10787829
OpenAlexW4390840541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.