Evidence map›Paper›PMID 38218918›Full record

ArticleScientific reports2024

Phytofabricated bimetallic synthesis of silver-copper nanoparticles using Aerva lanata extract to evaluate their potential cytotoxic and antimicrobial activities.

Gopishankar Thirumoorthy, Balamuralikrishnan Balasubramanian, Jincy A George, Aatika Nizam, Praveen Nagella, N Srinatha, Manikantan Pappuswamy, Amer M Alanazi, Arun Meyyazhagan, Kannan R R Rengasamy and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Gellan Gum/Alginate Films Containing BiogenicMolecules (Basel, Switzerland) · 2026
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  5. Myconanotechnology: evaluation of Ag-Cu bimetallic nanoparticles synthesized by Ganoderma aff. australe against pathogens and cancer cells.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Gopishankar Thirumoorthy *Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
Balamuralikrishnan Balasubramanian *Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, South Korea.
Jincy A GeorgeDepartment of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
Aatika NizamDepartment of Chemistry, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
Praveen NagellaDepartment of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
N SrinathaDepartment of Physics, RV Institute of Technology and Management, Bengaluru, 560 076, India.
Manikantan PappuswamyDepartment of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
Amer M AlanaziPharmaceutical Chemistry Department, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Arun MeyyazhaganDepartment of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India.
Kannan R R RengasamyLaboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India. ragupathi.rengasamy@nwu.ac.za.
Vasantha Veerappa LakshmaiahDepartment of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Bengaluru, Karnataka, 560029, India. vasantha.vl@christuniversity.in.
Christ University · INInstitute of Technology Management · INKing Saud University · SASaveetha University · INSejong University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we demonstrate the green synthesis of bimetallic silver-copper nanoparticles (Ag-Cu NPs) using Aerva lanata plant extract. These NPs possess diverse biological properties, including in vitro antioxidant, antibiofilm, and cytotoxic activities. The synthesis involves the reduction of silver nitrate and copper oxide salts mediated by the plant extract, resulting in the formation of crystalline Ag-Cu NPs with a face-centered cubic structure. Characterization techniques confirm the presence of functional groups from the plant extract, acting as stabilizing and reducing agents. The synthesized NPs exhibit uniform-sized spherical morphology ranging from 7 to 12 nm. They demonstrate significant antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, inhibiting extracellular polysaccharide secretion in a dose-dependent manner. The Ag-Cu NPs also exhibit potent cytotoxic activity against cancerous HeLa cell lines, with an inhibitory concentration (IC

Indexed as

Antineoplastic AgentsMetal NanoparticlesAnti-Bacterial AgentsAntioxidantsCopperHeLa CellsHumansHydrogen PeroxideMicrobial Sensitivity TestsPlant ExtractsAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsCopperHydrogen PeroxidePlant Extracts

Identifiers

PMID38218918
PMCPMC10787839
OpenAlexW4390838089

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.