Evidence map›Paper›PMID 38218874›Full record

SynthesisBMC oral health2024

Pharmacological therapy in the management of temporomandibular disorders and orofacial pain: a systematic review and meta-analysis.

Giuseppe Minervini, Rocco Franco, Salvatore Crimi, Marco Di Blasio, Cesare D'Amico, Vincenzo Ronsivalle, Gabriele Cervino, Alberto Bianchi, Marco Cicciù

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  16. Modern Approaches to the Treatment of Acute Facial Pain.Current pain and headache reports · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Giuseppe MinerviniSaveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India. Giuseppe.minervini@unicampania.it.
Rocco FrancoDepartment of Biomedicine and Prevention, University of University of Rome "Tor Vergata", 00100, Rome, Italy.
Salvatore CrimiDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, 95123, Catania, CT, Italy.
Marco Di BlasioDepartment of Medicine and Surgery, University Center of Dentistry, University of Parma, 43126, Parma, Italy. marco.diblasio@studenti.unipr.it.
Cesare D'AmicoSchool of Dentistry Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Via Consolare Valeria, 1, 98125, Messina, Italy.
Vincenzo RonsivalleDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, 95123, Catania, CT, Italy.
Gabriele CervinoSchool of Dentistry Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Via Consolare Valeria, 1, 98125, Messina, Italy.
Alberto BianchiDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, 95123, Catania, CT, Italy.
Marco CicciùDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, 95123, Catania, CT, Italy.
University of Catania · ITUniversity of Messina · ITSaveetha University · INUniversity of Parma · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemporomandibular disorders (TMD) are manifested by soreness in the jaw joint area and jaw muscles, clicks or creaks when opening or closing the mouth. All these symptoms can be disabling and occur during chewing and when the patient yawns or speaks. Several classes of drugs are used to treat symptoms. This review aims to assess which drug suits the different signs.

methodsPubmed, Web of Science and Lilacs were systematically searched until 01/02/2023. Clinical trials were selected that dealt with drugs used in temporomandibular dysfunction

resultsOut of 830 papers, eight studies were included. The Meta-Analysis with Continuous Outcomes with Pre-Calculated Effect Sizes resulted in the rejection that there is intergroup variability (p.0.74).

conclusionsTreatment of orofacial pain is still a significant challenge for dentistry. We can conclude that there is no drug of first choice in the treatment of temporomandibular pain. However, the clinician must distinguish the type of pain and the aetioloic cause of the pain so that the patient can be treated and managed pharmacologically.

Indexed as

Facial PainTemporomandibular Joint DisordersHumansMasticationTemporomandibular JointDrugsPharmacological treatmentTemporomandibular disease

Identifiers

PMID38218874
PMCPMC10787959
OpenAlexW4390837809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.