Evidence map›Paper›PMID 38217801›Full record

ArticleClinical oral investigations2024

Salivary and serum asprosin hormone levels in the 2018 EFP/AAP classification of periodontitis stages and body mass index status: a case-control study.

Sema Nur Sevinç Gül, Didem Özkal Eminoğlu, Esra Laloğlu, Tuğba Aydın, Alparslan Dilsiz

2 registry-linked trialsOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06627972 completednot on this map

Is there a relationship between periodontal condition and asprosin level in gingival crevicular fluid?

TypeobservationalSponsorMustafa Kemal UniversityRan2022 to 2022Enrolled75ConditionsPeriodontitis, Periodontal Health, Gingivitis
NCT06735313 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Salivary Asprosin, IL-39,IL-40 and IL-1β Levels in Diabetic Patients with Periodontitis

TypeinterventionalSponsorNecmettin Erbakan UniversityRan2025 to 2025Enrolled176ConditionsDiabetes Mellitus, Periodontal Disease, Asprosin, Interleukin 1-betaArmsPeriodontal examination and saliva collection
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sema Nur Sevinç GülDepartment of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey. semanursevinc@gmail.com.
Didem Özkal EminoğluDepartment of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
Esra LaloğluDepartment of Medical Biochemistry, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Tuğba AydınDepartment of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
Alparslan DilsizDepartment of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
Atatürk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA newly discovered adipokine known asprosin in serum and saliva in patients with periodontitis has not been explored. The aim of this study was to determine the relationship between serum and saliva asprosin levels and periodontitis by grouping it according to body mass index (BMI). MATERIALS AND

methodsThe study was conducted on 65 systemically healthy patients (35 patients with periodontitis (periodontitis group), 30 periodontally healthy patients (control group)). In each patient, age, BMI, and clinical periodontal parameters (plaque index (PI), gingival index (GI), probing depth (PD), and clinical attachment level (CAL)) were evaluated. Statistical analyses were conducted utilizing the Student t-test, ANOVA, and Pearson correlation analysis. For the significance level of the tests, p<0.05 were accepted.

resultsThe serum and saliva were collected to assess asprosin levels. Both the serum and saliva asprosin levels were statistically significantly higher in the periodontitis group than in the control group (p<0.001). Saliva and serum asprosin levels were directly proportional to the severity of the periodontal disease (p<0.05). Asprosin levels were higher in patients with a higher BMI (p<0.05).

conclusionAsprosin levels were increased in periodontitis, and even a high BMI status apparently affected the levels of this hormone. It is thought that asprosin may be a useful biomarker in evaluating the relationship between periodontal status and BMI. CLINICAL RELEVANCE: Asprosin may be a useful parameter as a biomarker of periodontal disease progression. However, BMI status should be considered when evaluating asprosin levels in patients with periodontitis.

Indexed as

Chronic PeriodontitisAdipokinesBiomarkersBody Mass IndexCase-Control StudiesFibrillin-1HumansSalivaAdipokinesBiomarkersFBN1 protein, humanFibrillin-1AdipokinesBody Mass IndexOral medicinePeriodontal diseasesPeriodontitis

Identifiers

PMID38217801
PMCPMC10787907
OpenAlexW4390840913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.