Evidence map›Paper›PMID 38217755›Full record

ReviewCurrent osteoporosis reports2024

Using AI to Write a Review Article Examining the Role of the Nervous System on Skeletal Homeostasis and Fracture Healing.

Murad K Nazzal, Ashlyn J Morris, Reginald S Parker, Fletcher A White, Roman M Natoli, Jill C Fehrenbacher, Melissa A Kacena

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Murad K NazzalDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Ashlyn J MorrisDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Reginald S ParkerDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Fletcher A WhiteDepartment of Anesthesia, Indiana University School of Medicine, Indianapolis, IN, USA.
Roman M NatoliDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Jill C FehrenbacherIndiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA. jfehrenb@iu.edu.
Melissa A KacenaDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. mkacena@iupui.edu.

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Comprehensive Training Program in Musculoskeletal ResearchT32AR065971 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI ALEXANDER G ROBLING · 2015 to 2026
$4.4M
Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging - LOADR01AG060621 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI KACENA, MELISSA A, LI, JILIANG · 2019 to 2023
$3.7M
Short-Term Training Program In Biomedical SciencesT35HL110854 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Brittney-Shea Herbert, Catherine Rufatto Sears · 2012 to 2026
$3.4M
The role of cell-specific TLR-4 signaling in oxaliplatin-induced peripheral neuropathyR01NS102415 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI WHITE, FLETCHER A · 2018 to 2022
$2.2M
Impact of TPO Treatment on Bone Healing and Angiogenesis in Type 2 DiabetesI01BX003751 · VA · RLR VA MEDICAL CENTER · PI KACENA, MELISSA A · 2017 to 2021
–
RR&D Research Career Scientist Award ApplicationIK6RX004809 · VA · RLR VA MEDICAL CENTER · PI KACENA, MELISSA A · 2023 to 2025
–
"Novel therapeutic approaches to improve fracture healing while reducing pain behavior"I01RX003552 · VA · RLR VA MEDICAL CENTER · PI KACENA, MELISSA A · 2022 to 2025
–
BLRD VA I01 BX003751BLRD VA I01 BX006399NCATS NIH HHS UL1 TR002529NHLBI NIH HHS T35 HL110854NIAMS NIH HHS T32 AR065971NIA NIH HHS R01 AG060621NIH HHS AG060621NIH HHS AR065971NIH HHS HL110854NINDS NIH HHS R01 NS102415RRD VA I01 RX003552RRD VA IK6 RX004809
6 · The paper itself

Abstract

purpose of reviewThree review articles have been written that discuss the roles of the central and peripheral nervous systems in fracture healing. While content among the articles is overlapping, there is a key difference between them: the use of artificial intelligence (AI). In one paper, the first draft was written solely by humans. In the second paper, the first draft was written solely by AI using ChatGPT 4.0 (AI-only or AIO). In the third paper, the first draft was written using ChatGPT 4.0 but the literature references were supplied from the human-written paper (AI-assisted or AIA). This project was done to evaluate the capacity of AI to conduct scientific writing. Importantly, all manuscripts were fact checked and extensively edited by all co-authors rendering the final manuscript drafts significantly different from the first drafts. RECENT

findingsUnsurprisingly, the use of AI decreased the time spent to write a review. The two AI-written reviews took less time to write than the human-written paper; however, the changes and editing required in all three manuscripts were extensive. The human-written paper was edited the most. On the other hand, the AI-only paper was the most inaccurate with inappropriate reference usage and the AI-assisted paper had the greatest incidence of plagiarism. These findings show that each style of writing presents its own unique set of challenges and advantages. While AI can theoretically write scientific reviews, from these findings, the extent of editing done subsequently, the inaccuracy of the claims it makes, and the plagiarism by AI are all factors to be considered and a primary reason why it may be several years into the future before AI can present itself as a viable alternative for traditional scientific writing.

Indexed as

Artificial IntelligenceFracture HealingHomeostasisHumansPeripheral Nervous SystemWritingAIArtificial intelligenceChatGPTFracture healingNeural regulationScientific writing

Identifiers

PMID38217755
PMCPMC10912134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.