Evidence map›Paper›PMID 38217733›Full record

SynthesisClinical oral investigations2024

Artificial intelligence for classification and detection of oral mucosa lesions on photographs: a systematic review and meta-analysis.

Rata Rokhshad, Hossein Mohammad-Rahimi, Jeffery B Price, Reyhaneh Shoorgashti, Zahra Abbasiparashkouh, Mahdieh Esmaeili, Bita Sarfaraz, Arad Rokhshad, Saeed Reza Motamedian, Parisa Soltani and 1 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Review
  7. AI-Powered Microscopic Diagnostic Techniques forJournal of dentistry (Shiraz, Iran) · 2026
    Article
  8. Application of artificial intelligence in oral potentially malignant disorders: current opinions and future barriers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  9. From Image to Diagnosis: Convolutional Neural Networks in Tongue Lesions.Journal of imaging informatics in medicine · 2026
    Article
  10. Review
  11. Review
  12. Review
  13. AI-assisted image analysis ofBioinformation · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Practice and challenge of age-friendly functional restoration of stomatognathic system based on the strategy of functional tooth loss.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rata RokhshadTopic Group Dental Diagnostics and Digital Dentistry, ITU/WHO Focus Group AI On Health, Berlin, Germany.
Hossein Mohammad-RahimiTopic Group Dental Diagnostics and Digital Dentistry, ITU/WHO Focus Group AI On Health, Berlin, Germany.
Jeffery B PriceDepartment of Oncology and Diagnostic Sciences, University of Maryland, School of Dentistry, Baltimore, Maryland 650 W Baltimore St, Baltimore, MD, 21201, USA.
Reyhaneh ShoorgashtiFaculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, 9Th Neyestan, Pasdaran, Tehran, Iran.
Zahra AbbasiparashkouhUniversity of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Mahdieh EsmaeiliFaculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, 9Th Neyestan, Pasdaran, Tehran, Iran.
Bita SarfarazSchool of Dentistry, Shahid Beheshti University of Medical Sciences, Daneshjoo Blvd, Evin, Shahid Chamran Highway, Tehran, Postal Code: 1983963113, Iran.
Arad RokhshadFaculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, 9Th Neyestan, Pasdaran, Tehran, Iran.
Saeed Reza MotamedianDentofacial Deformities Research Center, Research Institute of Dental Sciences & Department of Orthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Daneshjoo Blvd, Evin, Shahid Chamran Highway, Tehran, Postal Code: 1983963113, Iran. drmotamedian@gmail.com.ORCID http://orcid.org/0000-0001-7337-2145
Parisa SoltaniDepartment of Oral and Maxillofacial Radiology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Salamat Blv, Isfahan Dental School, Isfahan, Iran.
Falk SchwendickeTopic Group Dental Diagnostics and Digital Dentistry, ITU/WHO Focus Group AI On Health, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to review and synthesize studies using artificial intelligence (AI) for classifying, detecting, or segmenting oral mucosal lesions on photographs. MATERIALS AND

methodInclusion criteria were (1) studies employing AI to (2) classify, detect, or segment oral mucosa lesions, (3) on oral photographs of human subjects. Included studies were assessed for risk of bias using Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). A PubMed, Scopus, Embase, Web of Science, IEEE, arXiv, medRxiv, and grey literature (Google Scholar) search was conducted until June 2023, without language limitation.

resultsAfter initial searching, 36 eligible studies (from 8734 identified records) were included. Based on QUADAS-2, only 7% of studies were at low risk of bias for all domains. Studies employed different AI models and reported a wide range of outcomes and metrics. The accuracy of AI for detecting oral mucosal lesions ranged from 74 to 100%, while that for clinicians un-aided by AI ranged from 61 to 98%. Pooled diagnostic odds ratio for studies which evaluated AI for diagnosing or discriminating potentially malignant lesions was 155 (95% confidence interval 23-1019), while that for cancerous lesions was 114 (59-221).

conclusionsAI may assist in oral mucosa lesion screening while the expected accuracy gains or further health benefits remain unclear so far. CLINICAL RELEVANCE: Artificial intelligence assists oral mucosa lesion screening and may foster more targeted testing and referral in the hands of non-specialist providers, for example. So far, it remains unclear if accuracy gains compared with specialized can be realized.

Indexed as

Artificial IntelligenceMouth MucosaHumansReferral and ConsultationArtificial intelligenceDeep learningHead and neck cancerMachine learningOral cancerOral neoplasmsPrecancerous conditions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.