Evidence map›Paper›PMID 38217683›Full record

ArticleDigestive diseases and sciences2024

A Prospective Open-Label Dose-Response Study to Correct Vitamin D Deficiency in Cirrhosis.

Chip A Bowman, Kian Bichoupan, Shai Posner, Emily Schonfeld, Alexis Pappas, Mark Woodward, Thomas Schiano, Andrea D Branch

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Chip A BowmanDivision of Digestive and Liver Diseases, Department of Medicine, Columbia University New York Presbyterian, New York, NY, USA.
Kian BichoupanDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA.
Shai PosnerDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA.
Emily SchonfeldDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA.
Alexis PappasDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA.
Mark WoodwardThe George Institute for Global Health, School of Public Health, Imperial College London, London, UK.
Thomas SchianoDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA.
Andrea D BranchDivision of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY, 10029, USA. Andrea.branch@mssm.edu.ORCID http://orcid.org/0000-0003-2865-3188
Icahn School of Medicine at Mount Sinai · USTexas Health Dallas · USThe George Institute for Global Health · GB

Funding

Health Services Research Programme R01DA031095Health Services Research Programme R01DK090317
6 · The paper itself

Abstract

backgroundPatients with advanced liver disease often have vitamin D deficiency, but the daily dosages of vitamin D

objectiveWe aimed to establish the dose-response relationship between vitamin D

designAn open-label study of orally-administered vitamin D

resultsAmong the 48 patients, 39 (81%) had 25(OH)D > 20 ng/mL while on supplements, and none experienced hypercalcemia. The magnitude of the increase in 25(OH)D was approximately twofold greater in patients receiving the higher dose. The mean incremental increase was 5.1 ng/ml ± 3.9 of 25(OH)D per 1000 IU/d of vitamin D

conclusionsA two-tiered dosing regimen of daily oral vitamin D

Indexed as

CholecalciferolVitamin D DeficiencyAdultDietary SupplementsHumansLiver CirrhosisProspective StudiesVitamin DCholecalciferolVitamin DCholecalciferolCirrhosisSupplementationTransplantVitamin D

Identifiers

PMID38217683
OpenAlexW4390838062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.