Evidence map›Paper›PMID 38217602›Full record

ArticleJournal of Alzheimer's disease : JAD2024

FACEmemory®, an Innovative Online Platform for Episodic Memory Pre-Screening: Findings from the First 3,000 Participants.

Montserrat Alegret, Fernando García-Gutiérrez, Nathalia Muñoz, Ana Espinosa, Gemma Ortega, Núria Lleonart, Isabel Rodríguez, Maitee Rosende-Roca, Vanesa Pytel, Yahveth Cantero-Fortiz and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. FACEmemoryJournal of clinical medicine · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Montserrat AlegretAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Fernando García-GutiérrezAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Nathalia MuñozAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Ana EspinosaAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Gemma OrtegaAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Núria LleonartAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Isabel RodríguezAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Maitee Rosende-RocaAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Vanesa PytelAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Yahveth Cantero-FortizAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Dorene M RentzDepartment of Neurology, Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston, MA, USA.
Marta MarquiéAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Sergi ValeroAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Agustín RuizAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Christopher ButlerAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Mercè BoadaAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.
Universitat Internacional de Catalunya · ESInstituto de Salud Carlos III · ESBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe FACEmemory® online platform comprises a complex memory test and sociodemographic, medical, and family questions. This is the first study of a completely self-administered memory test with voice recognition, pre-tested in a memory clinic, sensitive to Alzheimer's disease, using information and communication technologies, and offered freely worldwide.

objectiveTo investigate the demographic and clinical variables associated with the total FACEmemory score, and to identify distinct patterns of memory performance on FACEmemory.

methodsData from the first 3,000 subjects who completed the FACEmemory test were analyzed. Descriptive analyses were applied to demographic, FACEmemory, and medical and family variables; t-test and chi-square analyses were used to compare participants with preserved versus impaired performance on FACEmemory (cut-off = 32); multiple linear regression was used to identify variables that modulate FACEmemory performance; and machine learning techniques were applied to identify different memory patterns.

resultsParticipants had a mean age of 50.57 years and 13.65 years of schooling; 64.07% were women, and 82.10% reported memory complaints with worries. The group with impaired FACEmemory performance (20.40%) was older, had less schooling, and had a higher prevalence of hypertension, diabetes, dyslipidemia, and family history of neurodegenerative disease than the group with preserved performance. Age, schooling, sex, country, and completion of the medical and family history questionnaire were associated with the FACEmemory score. Finally, machine learning techniques identified four patterns of FACEmemory performance: normal, dysexecutive, storage, and completely impaired.

conclusionsFACEmemory is a promising tool for assessing memory in people with subjective memory complaints and for raising awareness about cognitive decline in the community.

Indexed as

Alzheimer DiseaseCognitive DysfunctionMemory, EpisodicNeurodegenerative DiseasesCognitionFemaleHumansMaleNeuropsychological TestsAlzheimer’s diseasecommunitycomputerized assessmentearly detectionmemorymemory impairmentnew technologiespatient engagementsubjective memory complaints

Identifiers

PMID38217602
PMCPMC10977414
OpenAlexW4390745753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.