Evidence map›Paper›PMID 38217567›Full record

ArticleRadiation and environmental biophysics2024

Forty-eight-year follow-up of a female worker exposed to highly enriched uranium via chronic and acute inhalation.

Maia Avtandilashvili, Sergey Y Tolmachev

Abstract read
PubMed Publisher
In one paragraph

Article in Radiation and environmental biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Distribution of plutonium and radium in the human heart.Journal of radiological protection : official journal of the Society for Radiological Protection · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maia AvtandilashviliUnited States Transuranium and Uranium Registries, College of Pharmacy and Pharmaceutical Sciences, Washington State University, 1845 Terminal Drive, Suite 201, Richland, WA, 99354-4959, USA. m.avtandilashvili@wsu.edu.ORCID 0000-0001-9400-8617
Sergey Y TolmachevUnited States Transuranium and Uranium Registries, College of Pharmacy and Pharmaceutical Sciences, Washington State University, 1845 Terminal Drive, Suite 201, Richland, WA, 99354-4959, USA.ORCID 0000-0003-0077-106X
Washington State University Tri-Cities · US

Funding

U.S. Department of Energy DE-HS0000073
6 · The paper itself

Abstract

The United States Transuranium and Uranium Registries (USTUR) is a unique resource of data and materials for studying biokinetics of uranium in the human body. In this study, bioassay data and post-mortem organ activities from a female whole-body USTUR donor who was exposed to highly enriched uranium were analyzed using the IMBA Professional Plus® software to derive the best estimate of the total intake. The resulting radiation doses delivered to this individual's whole body and major target organs were calculated from estimated intake based on case-specific dose coefficients derived using the AIDE® software. Both intake and dose calculations were carried out using the biokinetic and dosimetric models recommended by the International Commission on Radiological Protection (ICRP) in its Occupational Intakes of Radionuclides publication series. Different exposure scenarios including chronic and acute inhalation intakes were tested. A combination of a chronic inhalation intake and two acute inhalation intakes appears to best describe the bioassay data. To fit this female individual's autopsy data, the transfer rate from the liver to the blood was increased by a factor of 8 and the transfer rate from the kidneys to the blood was decreased by a factor of 2.2. This resulted in the best fit to all data (p = 0.519). The total intake was estimated to be 44.1 kBq, and the committed effective dose was 211 mSv with 96.8% contributed by

Indexed as

Occupational ExposureUraniumFemaleFollow-Up StudiesHumansMaleRadiation DosageRadioisotopesRadiometrySoftwareRadioisotopesUraniumAutopsy tissue analysisBiokinetic modelingFemaleHighly enriched uraniumInhalation

Identifiers

PMID38217567
OpenAlexW4390839527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.