Evidence map›Paper›PMID 38217018›Full record

ReviewInfectious agents and cancer2024

A systematic review of endometrial cancer clinical research in Africa.

Chidinma P Anakwenze, Agnes Ewongwo, Louisa Onyewadume, Ademola Oyekan, Chinelo Onwualu Chigbo, Luca Valle, Yimin Geng, Paul Olapade, Kenechukwu Okwunze, Nwamaka Lasebikan and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Infectious agents and cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chidinma P AnakwenzeDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA. cpanakwenze@mdanderson.org.ORCID http://orcid.org/0000-0003-1324-4410
Agnes EwongwoDepartment of Radiation Oncology, Stanford University, Palo Alto, CA, USA.
Louisa OnyewadumeHarvard University School of Public Health, Boston, MA, USA.
Ademola OyekanDepartment of Radiation and Clinical Oncology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Chinelo Onwualu ChigboDepartment of Radiation and Clinical Oncology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Luca ValleDepartment of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.
Yimin GengResearch Medical Library, MD Anderson Cancer Center, Houston, TX, USA.
Paul OlapadeCollege of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Kenechukwu OkwunzeCollege of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Nwamaka LasebikanDepartment of Radiation and Clinical Oncology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Anuja JhingranDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA.
Onyinye D Balogun *Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA.
Atara Ntekim *Department of Radiation Oncology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen in Africa are experiencing a rising burden of endometrial cancer. Research and investment to improve treatment and outcomes are critically needed. We systematically reviewed and characterized endometrial cancer-related research within a clinically relevant context to help organize and assess existing endometrial cancer research in Africa.

methodsAccording to PRISMA guidelines, we searched online databases for published endometrial cancer articles from African countries from January 1, 2011, to July 20, 2021. Based on our inclusion and exclusion criteria, independent reviewers documented the study design, country/region, human development index, focus of research, type of interventions performed, and histologic and molecular type to illustrate the breadth of research coverage in each region.

resultsA total of 18 research articles were included. With an average Human Development Index (HDI) in Africa of 0.536, the average HDI of the represented countries in this study was 0.709. The majority (88.9%) of prospective endometrial cancer research articles in Africa were from North Africa, with Egypt encompassing 83.3% of the papers. Most of these studies focused on endometrial cancer diagnosis. Research on the treatment of endometrial cancer is still emerging (33% of papers). Of all included articles, only 11.1% represented Sub-Saharan Africa, where the majority population of black Africans reside.

conclusionsEndometrial cancer research in Africa is extremely limited, with the majority being concentrated in African countries with higher HDIs. As the incidence of endometrial cancer rises in Sub-Saharan Africa, there is a pressing need for more prospective clinical research to tackle the growing disease burden and improve outcomes.

Indexed as

AfricaEndometrial cancerSystematic review

Identifiers

PMID38217018
PMCPMC10787484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.