Evidence map›Paper›PMID 38216859›Full record

ArticleBMC neurology2024

Efficacy of rTMS for poststroke epilepsy and its effects on patients' cognitive function and depressive status.

Minting Hu, Bailing Qin, Tong Li, Chunyan Wei, Dajing Su, Zuocai Tan

Abstract read
In one paragraph

Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Minting Hu *Department of Neurology, The Second People's Hospital of Nanning, Nanning, China.
Bailing Qin *Department of Neurology, The Second People's Hospital of Nanning, Nanning, China. qingying8261@126.com.
Tong LiDepartment of Neurology, The Second People's Hospital of Nanning, Nanning, China.
Chunyan WeiDepartment of Neurology, The Second People's Hospital of Nanning, Nanning, China.
Dajing SuDepartment of Neurology, The Second People's Hospital of Nanning, Nanning, China.
Zuocai TanDepartment of Neurology, The Second People's Hospital of Nanning, Nanning, China.

Funding

Scientific research project of Guangxi District Health Care Committee Z20210233
6 · The paper itself

Abstract

objectiveThis study aimed to investigate the efficacy of rTMS in the treatment of poststroke epilepsy and the effect of rTMS on patients' cognitive function and depressive status.

methodsOne hundred and twenty-one poststroke epilepsy patients with mild cognitive impairment and depressive status admitted to the Department of Neurology of the Second People's Hospital of Nanning from January 1, 2017, to April 31, 2023, were selected and divided into the rTMS treatment group (treated group) and the control group. MMSE scores and HAMD scores were recorded before and after treatment. The frequency of EEG spiky waves recorded before and after treatment within 24 h and the frequency of any clinical seizure form (the number of clinical seizures within 1 month after treatment) and changes in observed indices before and after treatment were calculated. The differences between the data of the two groups were analyzed, to further assess the efficacy of rTMS in the treatment of poststroke epilepsy and the rTMS' effects on cognition and depression.

resultsCompared with drug treatment alone, rTMS significantly decreased clinical seizures and epileptiform discharges after stroke, especially in patients with lesions in the frontal, temporal, and parietal lobes. Compared with drug treatment alone, rTMS treatment can effectively reduce cognitive impairment and mood disorders, such as depression, especially for patients with lesions in the frontal and temporal lobes. The results of this experiment suggest that rTMS treatment does not increase adverse effects.

conclusionrTMS reduces clinical seizures while improving cognitive impairment and depression in patients with epilepsy. Therefore, we suggest that low-frequency rTMS can be used as an adjunctive treatment for patients with epilepsy and provide some ideas and references for the treatment of epilepsy with cognitive impairment and depression.

Indexed as

EpilepsyCognitionHumansSeizuresTranscranial Magnetic StimulationTreatment OutcomeCognitive impairmentDepressionHAMDMMSEPoststroke epilepsyRepetitive transcranial magnetic stimulation (rTMS)

Identifiers

PMID38216859
PMCPMC10785375

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.