Evidence map›Paper›PMID 38216820›Full record

ArticleDermatology and therapy2024

Redefining Disease Severity with Special Area Involvement and Reflecting on Treatment Patterns in a Real-World Psoriasis Population.

Mary E Horner, Kate K Orroth, Junjie Ma, Yinkang Duan, Myriam Cordey

Abstract read
In one paragraph

Article in Dermatology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary E HornerDermatology Consultants of Sacramento, 5340 Elvas Ave, Ste 600, Sacramento, CA, 95819, USA. maryehorner@gmail.com.
Kate K OrrothAmgen Inc., Thousand Oaks, CA, USA.ORCID http://orcid.org/0000-0002-4950-3149
Junjie MaAmgen Inc., Thousand Oaks, CA, USA.ORCID http://orcid.org/0000-0002-6249-876X
Yinkang DuanSimulstat Inc., Solana Beach, CA, USA.
Myriam CordeyAmgen Inc., Thousand Oaks, CA, USA.ORCID http://orcid.org/0009-0004-1797-0510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe International Psoriasis Council (IPC) recommends an approach that considers body surface area (BSA), involvement in special areas, and treatment history for classifying patients as candidates for topical or systemic treatment. This study aimed to quantify the burden of psoriasis by describing BSA distribution, special area involvement, and treatments in a real-world population.

methodsThis retrospective cohort study included patients with psoriasis from the Optum

resultsAmong eligible patients (N = 5120), mean age was 51.4 years and 49.3% were women. The majority of patients (78.9%) were treated with any topical. Proportions of patients with BSA < 3%, 3-10%, and > 10% were 23.4%, 41.9%, and 34.6%, respectively; proportions with 0, 1, and 2

conclusionThe IPC classification can likely identify many more patients who may benefit from systemic therapy than BSA alone.

Indexed as

Autoinflammatory diseaseBody surface areaElectronic health recordsImmunotherapyPsoriasisRetrospective studies

Identifiers

PMID38216820
PMCPMC10828323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.