Evidence map›Paper›PMID 38216723›Full record

ArticleEuropean journal of applied physiology2024

The polymorphism T1470A of the SLC16A1 gene is associated with the lactate and ventilatory thresholds but not with fat oxidation capacity in young men.

Isaac A Chávez-Guevara, Everardo González-Rodríguez, Verónica Moreno-Brito, Jorge A Pérez-León, Francisco J Amaro-Gahete, Marina Trejo-Trejo, Arnulfo Ramos-Jiménez

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Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isaac A Chávez-GuevaraFaculty of Sports Campus Ensenada, Autonomous University of Baja California, Baja California, Mexico.ORCID http://orcid.org/0000-0001-9773-5043
Everardo González-RodríguezFaculty of Medicine and Biomedical Sciences, Autonomous University of Chihuahua, Chihuahua, Mexico.ORCID http://orcid.org/0000-0003-0401-0073
Verónica Moreno-BritoFaculty of Medicine and Biomedical Sciences, Autonomous University of Chihuahua, Chihuahua, Mexico.ORCID http://orcid.org/0000-0002-6094-7832
Jorge A Pérez-LeónDepartment of Chemical Sciences, Biomedical Sciences Institute, Ciudad Juarez Autonomous University, Chihuahua, Mexico.ORCID http://orcid.org/0000-0002-9148-2054
Francisco J Amaro-GaheteDepartment of Physiology, Faculty of Medicine, University of Granada, 18071, Granada, Spain.ORCID http://orcid.org/0000-0002-7207-9016
Marina Trejo-TrejoFaculty of Sports Campus Mexicali, Autonomous University of Baja California, Baja California, Mexico.
Arnulfo Ramos-JiménezDepartment of Health Sciences, Biomedical Sciences Institute, Ciudad Juarez Autonomous University, Chihuahua, Mexico. aramos@uacj.mx.ORCID http://orcid.org/0000-0002-4347-6725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the association of the single nucleotide polymorphism A1470T in the SLC16A1 gene with blood lactate accumulation during a graded exercise test and its associated metaboreflex.

methodsForty-six Latin-American men (Age: 27 ± 6 years; Body fat: 17.5 ± 4.7%) performed a graded exercise test on a treadmill for the assessment of maximal oxygen uptake (VO

resultsGenotypes distribution were in Hardy-Weinberg equilibrium (X

conclusionIndependently of cardiorespiratory fitness, the A1470T polymorphism is associated to blood lactate accumulation and its associated ventilatory response during submaximal intensity exercise. However, the A1470 polymorphism does not influence fat oxidation capacity during exercise in young men.

Indexed as

Lactic AcidMonocarboxylic Acid TransportersPolymorphism, Single NucleotideSymportersAdultAnaerobic ThresholdExerciseExercise TestGenotypeHumansLipid MetabolismMaleMonocarboxylate Transport Protein 1Oxidation-ReductionOxygen ConsumptionLactic AcidMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymportersEnergy metabolismHuman geneticsIndirect calorimetryPhysical enduranceSports medicine

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.