Evidence map›Paper›PMID 38216647›Full record

Trial reportEuropean journal of clinical nutrition2024

Monounsaturated fat-rich diet reduces body adiposity in women with obesity, but does not influence energy expenditure and substrate oxidation: a parallel randomized controlled clinical trial.

Marcelly Cunha Oliveira Dos Santos Lopes, Vanessa Chaia Kaippert, Louise Crovesy, Denise Pires de Carvalho, Eliane Lopes Rosado

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02656940 (Effects of Dietary Lipid Modulation in Energy Expenditure, Body Composition, Obesity-related Biomarkers and Gene Expression of Peroxisome Proliferator-Activated Receptors Alpha and Gamma 2 in Adipose Tissue of Obese Women), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02656940 nacompletednot on this map

Effects of Dietary Lipid Modulation in Energy Expenditure, Body Composition, Obesity-related Biomarkers and Gene Expression of Peroxisome Proliferator-Activated Receptors Alpha and Gamma 2 in Adipose Tissue of Obese Women

TypeinterventionalSponsorUniversidade Federal do Rio de JaneiroRan2013 to 2014Enrolled32ConditionsObesityArmsGroup 1 - diet rich in n-3 and n-6 PUFA, Group 2 - diet rich in MUFA, Group 3 - Placebo group
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Calafate (Antioxidants (Basel, Switzerland) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Marcelly Cunha Oliveira Dos Santos LopesLaboratory of Nutritional Assessment, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Sector J, 2nd floor, University City, Rio de Janeiro, 21941-902, Brazil. marcelly@nutricao.ufrj.br.ORCID http://orcid.org/0000-0002-2068-9058
Vanessa Chaia KaippertLaboratory of Nutritional Assessment, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Sector J, 2nd floor, University City, Rio de Janeiro, 21941-902, Brazil.
Louise CrovesyNutrition and Dietetics Department, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Sector J, 2nd floor, University City, Rio de Janeiro, 21941-902, Brazil.
Denise Pires de CarvalhoLaboratory of Endocrine Physiology Doris Rosenthal, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Sector G, University City, Rio de Janeiro, 21941-902, Brazil.
Eliane Lopes RosadoNutrition and Dietetics Department, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Sector J, 2nd floor, University City, Rio de Janeiro, 21941-902, Brazil.
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is an important and growing health problem whose treatment involves dietary changes. In this context, studying the role of macronutrients in weight loss is required in order to understand which strategies may be applied for weight loss. We aimed to evaluate the effects of diets rich in polyunsaturated (PUFAs) and monounsaturated fatty acids (MUFAs) on resting energy expenditure (REE), substrate oxidation, and weight loss in women with obesity.

methodsRandomized, controlled, single blind, parallel-group clinical trial was conducted for 60 days. Participants (n = 32) were divided into three groups: G1= normocaloric PUFAs-rich diet (12% of total energy expenditure (TEE), 10% of n-6 and up to 2% of n-3); G2= normocaloric MUFAs-rich diet (15-20% TEE); and G3= maintenance of the usual diet. Anthropometric and metabolic variables (REE and substrate oxidation by indirect calorimetry) were evaluated.

resultsG2 decreased body weight (-1.92 ± 1.99 kg, P = 0.02), body mass index (BMI) (-0.69 ± 0.70 kg/m

conclusionMUFAs-rich diet reduces body weight, BMI, body fat, and WC. CLINICAL TRIALS: NCT02656940. CLINICAL

trial registrationClinical Trials: NCT02656940.

Indexed as

AdiposityDietary FatsBody WeightDietEnergy MetabolismFatty Acids, MonounsaturatedFatty Acids, UnsaturatedFemaleHumansObesitySingle-Blind MethodWeight LossDietary FatsFatty Acids, MonounsaturatedFatty Acids, Unsaturated

Identifiers

PMID38216647
OpenAlexW4390818112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.