Evidence map›Paper›PMID 38216522›Full record

ArticleAutism research : official journal of the International Society for Autism Research2024

Accuracy of initial diagnostic impressions of autism in toddlers and behaviors that inform these impressions.

Rebecca P Thomas, Ashley de Marchena, Andrea Trubanova Wieckowski, Aubyn Stahmer, Stephanie Milan, Jeffrey D Burke, Marianne L Barton, Diana L Robins, Deborah A Fein

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In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rebecca P ThomasDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-7159-7532
Ashley de MarchenaA.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4186-6065
Andrea Trubanova WieckowskiA.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-5811-3460
Aubyn StahmerDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California, Davis, Sacramento, California, USA.
Stephanie MilanDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.
Jeffrey D BurkeDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.
Marianne L BartonDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.
Diana L RobinsA.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-7791-7031
Deborah A FeinDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.
University of Connecticut · USDrexel University · USUniversity of California, Davis · US

Funding

Extending the Early Start Denver Model to Young Children with Down SyndromeR01MH115715 · NIMH · DREXEL UNIVERSITY · PI ROBINS, DIANA L · 2017 to 2021
$12.2M
NIH HHS R01MH115715NIMH NIH HHS R01 MH115715
6 · The paper itself

Abstract

Clinicians form initial impressions about a child's diagnosis based on behavioral features, but research has not yet identified specific behaviors to guide initial diagnostic impressions. Participants were toddlers (N = 55, mean age 22.9 months) from a multi-site early detection study, referred for concern for ASD due to screening or parent/provider concern. Within 5 min of meeting a child, clinicians noted ASD or non-ASD impression, confidence in impression, and behaviors that informed their impression. These clinicians also determined final diagnoses for each child. When a child's final diagnosis was ASD (n = 35), senior clinicians formed an initial impression of ASD in 22 cases (63%) but missed 13 cases (37%). When final diagnosis was non-ASD (n = 20), senior clinicians made an initial impression of non-ASD in all cases (100%). Results were similar among junior clinicians. Senior and junior clinicians used the same behaviors to form accurate impressions of ASD and non-ASD: social reciprocity, nonverbal communication, and eye contact. Senior clinicians additionally used focus of attention when forming accurate impressions of ASD and non-ASD; junior clinicians used this behavior only when forming accurate non-ASD impressions. Clinicians' initial impressions of ASD are very likely to be consistent with final diagnoses, but initial impressions of non-ASD need follow-up. Toddlers who show all four atypical behaviors (social reciprocity, nonverbal communication, eye contact, and focus of attention) might receive expedited ASD diagnoses. However, presence of apparently typical behaviors should not rule out ASD; for some children a longer evaluation is necessary to allow for more opportunities to observe subtle social behavior.

Indexed as

Autism Spectrum DisorderAutistic DisorderChild Development Disorders, PervasiveChildChild, PreschoolHumansInfantMental ProcessesSocial Behaviorautism spectrum disorderdiagnostic confidencediagnostic decision‐makinginitial impressionstoddlers

Identifiers

PMID38216522
PMCPMC11025624
OpenAlexW4390810715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.