Evidence map›Paper›PMID 38216520›Full record

ArticleJournal of veterinary internal medicine

Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation.

Jordan Schachar, Alan Bocage, Nathan C Nelson, Peter J Early, Christopher L Mariani, Natasha J Olby, Karen R Muñana

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jordan SchacharDepartment of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.
Alan BocageDepartment of Molecular and Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.
Nathan C NelsonDepartment of Molecular and Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.ORCID https://orcid.org/0000-0003-3765-1694
Peter J EarlyDepartment of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.ORCID https://orcid.org/0000-0003-3399-8500
Christopher L MarianiDepartment of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.ORCID https://orcid.org/0000-0003-3228-6536
Natasha J OlbyDepartment of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.ORCID https://orcid.org/0000-0003-1349-3484
Karen R MuñanaDepartment of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, North Carolina 27606, USA.ORCID https://orcid.org/0000-0001-9592-6276
North Carolina State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntervertebral disc herniation (IVDH) is the most common spinal cord disease in dogs. Little information is available regarding the clinical presentation of nerve root signature (NRS) associated with cervical IVDH. HYPOTHESIS/

objectiveTo detail the clinical and magnetic resonance imaging (MRI) findings in dogs with NRS associated with cervical IVDH. ANIMALS: Forty-seven client-owned dogs presenting with thoracic limb NRS and MRI confirmed IVDH.

methodsMedical records from 2010 to 2020 were retrospectively reviewed for dogs that met inclusion criteria. Imaging studies were evaluated by 2 individuals to characterize location and severity of neural tissue compression.

resultsChondrodystrophoid dogs comprised the majority of the study cohort, with dachshund the most common breed (n = 10). Three-quarters of dogs were ≥7 years of age. Interobserver agreement was moderate or good for all of the imaging variables evaluated. The C6-C7 intervertebral disc space was significantly overrepresented (P = .01), comprising 32% (15/47) of the affected discs. However, 42% (20/47) of cases involved C2-C3 though C4-C5 disc sites. Disc material was more frequently located laterally compared to medially within the vertebral canal (P = .0005), and to be associated with compression of the nerve root at the level of the intervertebral foramen (P = .012). CONCLUSION/CLINICAL IMPORTANCE: NRS is most commonly associated with lateralized or foraminal cervical disc herniations. It is most prevalent with C6-C7 intervertebral disc involvement, suggesting that there might be unique anatomic factors that contribute to development of NRS at this site, but can be a clinical manifestation of IVDH occurring anywhere along the cervical spine.

Indexed as

Dog DiseasesIntervertebral DiscIntervertebral Disc DegenerationIntervertebral Disc DisplacementAnimalsCervical VertebraeDogsHumansMagnetic Resonance ImagingRetrospective Studiescervical radiculopathyintraforaminal disc herniationmagnetic resonance imagingthoracic limb lameness

Identifiers

PMID38216520
PMCPMC10937489
OpenAlexW4390812370

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.