Evidence map›Paper›PMID 38216239›Full record

Trial reportBehavior therapy2024

Reciprocal and Indirect Effects Among Intervention, Perceived Social Support, and Anxiety Sensitivity Within a Randomized Controlled Trial for Anxiety Disorders.

Allison V Metts, Peter Roy-Byrne, Murray B Stein, Cathy D Sherbourne, Alexander Bystritsky, Michelle G Craske

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Behavior therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Allison V MettsUniversity of California, Los Angeles.
Peter Roy-ByrneUniversity of Washington School of Medicine, Seattle.
Murray B SteinUniversity of California San Diego.
Cathy D SherbourneRAND Corporation, Santa Monica.
Alexander BystritskyUniversity of California, Los Angeles.
Michelle G CraskeUniversity of California, Los Angeles. Electronic address: MCraske@mednet.ucla.edu.

Funding

CALM: Improving Primary Care Anxiety OutcomesU01MH057835 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2005 to 2009
$3.3M
CALM: IMPROVING PRIMARY CARE ANXIETY OUTCOMESU01MH070018 · NIMH · RAND CORPORATION · PI SHERBOURNE, CATHY D · 2005 to 2009
$3.1M
CALM: Improving Primary Care Anxiety OutcomesU01MH058915 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CRASKE, MICHELLE G · 2005 to 2009
$3.0M
CALM: Improving Primary Care OutcomesU01MH057858 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2005 to 2009
$2.4M
CALM: Improving Primary Care Anxiety OutcomesU01MH070022 · NIMH · UNIV OF ARKANSAS FOR MED SCIS · PI SULLIVAN, JAN GREER · 2005 to 2009
$2.3M
Improving Patient Outcomes in Anxiety DisordersK24MH064122 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2001 to 2011
$1.3M
Treating Anxiety in Public Sector Medical SettingsK24MH065324 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2003 to 2007
$661k
NIMH NIH HHS K24 MH064122NIMH NIH HHS K24 MH065324NIMH NIH HHS U01 MH057835NIMH NIH HHS U01 MH057858NIMH NIH HHS U01 MH058915NIMH NIH HHS U01 MH070018NIMH NIH HHS U01 MH070022
6 · The paper itself

Abstract

Social support may facilitate adaptive reappraisal of stressors, including somatic symptoms. Anxiety sensitivity refers to negative beliefs about somatic symptoms of anxiety, which may influence one's perception of social support. Evidence-based treatment may impact these associations. The current longitudinal study evaluated reciprocal relationships between perceived social support and anxiety sensitivity, and explored indirect intervention effects, in a randomized controlled trial for anxiety disorders that compared cognitive behavioral therapy with or without medications (CALM) to usual care. Data collected over 18 months from 940 primary care patients were examined in random intercept cross-lagged panel models. There were significant reciprocal associations between perceived social support increases and anxiety sensitivity decreases over time. There were significant indirect effects from intervention to perceived social support increases through anxiety sensitivity decreases and from intervention to anxiety sensitivity decreases through perceived social support increases. These data suggest that, relative to usual care, CALM predicted changes in one construct, which predicted subsequent changes in the other. Secondary analyses revealed an influence of anxiety and depressive symptoms on reciprocal associations and indirect effects. Findings suggest that future treatments could specifically address perceived social support to enhance reappraisal of somatic symptoms, and vice versa.

Indexed as

Medically Unexplained SymptomsAnxietyAnxiety DisordersDepressionHumansLongitudinal StudiesSocial Supportanxietyanxiety sensitivitycognitive behavioral therapydepressionsocial support

Identifiers

PMID38216239
PMCPMC13390608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.