Evidence map›Paper›PMID 38216155›Full record

ArticleJournal of medical radiation sciences2024

Estimation and comparison of the effective dose and lifetime attributable risk of thyroid cancer between males and females in routine head computed tomography scans: a multicentre study.

Daryoush Khoramian, Mohammad Haghparast, Adnan Honardari, Ebrahim Nouri, Esmail Ranjbar, Razagh Abedi-Friouzjah, Shiva Zarifi, Choirul Anam, Milad Najafzadeh, Mahdieh Afkhami-Ardakni

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Journal of medical radiation sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daryoush KhoramianThe Advocate Centre for Clinical Research, Ayatollah Yasrebi Hospital, Kashan, Iran.
Mohammad HaghparastDepartment of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Adnan HonardariDepartment of Radiology, Faculty of Para-Medicine, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran.
Ebrahim NouriDepartment of Radiology, Faculty of Para-Medicine, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran.
Esmail RanjbarDepartment of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Razagh Abedi-FriouzjahCellular and Molecular Research Centre, Yasuj University of Medical Sciences, Yasuj, Iran.
Shiva ZarifiRadiation Oncology Department, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Choirul AnamDepartment of Physics, Faculty of Mathematics and Sciences, Diponegoro University, Semarang, Indonesia.
Milad NajafzadehDepartment and Research Centre of Medical Physics, Mashhad University of Medical Science, Mashhad, Iran.ORCID https://orcid.org/0000-0003-1681-4837
Mahdieh Afkhami-ArdakniDepartment of Radiology, Faculty of Para-Medicine, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran.

Funding

Hormozgan University of Medical Sciences 980128
6 · The paper itself

Abstract

introductionA significant number of head computed tomography (CT) scans are performed annually. However, due to the close proximity of the thyroid gland to the radiation field, this procedure can expose the gland to ionising radiation. Consequently, this study aimed to estimate organ dose, effective dose (ED) and lifetime attributable risk (LAR) of thyroid cancer from head CT scans in adults.

methodsHead CT scans of 74 patients (38 males and 36 females) were collected using three different CT scanners. Age, sex, and scanning parameters, including scan length, tube current-time product (mAs), pitch, CT dose index, and dose-length product (DLP) were collected. CT-Expo software was used to calculate thyroid dose and ED for each patient based on scan parameters. LARs were subsequently computed using the methodology presented in the Biologic Effects of Ionizing Radiation (BEIR) Phase VII report.

resultsAlthough the mean thyroid organ dose (2.66 ± 1.03 mGy) and ED (1.6 ± 0.4 mSv) were slightly higher in females, these differences were not statistically significant compared to males (mean thyroid dose, 2.52 ± 1.31 mGy; mean ED, 1.5 ± 0.4 mSv). Conversely, there was a significant difference between the mean thyroid LAR of females (0.91 ± 1.35) and males (0.20136 ± 0.29) (P = 0.001). However, the influencing parameters were virtually identical for both groups.

conclusionsThe study's results indicate that females have a higher LAR than males, which can be attributed to higher radiation sensitivity of the thyroid in females. Thus, additional care in the choice of scan parameters and irradiated scan field for female patients is recommended.

Indexed as

Radiation DosageThyroid NeoplasmsTomography, X-Ray ComputedAdultAgedAged, 80 and overFemaleHeadHumansMaleMiddle AgedThyroid GlandCT scaneffective doseheadlifetime attributable riskthyroid dose

Identifiers

PMID38216155
PMCPMC11177018

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