Evidence map›Paper›PMID 38215909›Full record

ArticleMucosal immunology2024

A bacterial vesicle-based pneumococcal vaccine against influenza-mediated secondary Streptococcus pneumoniae pulmonary infection.

Saugata Majumder, Peng Li, Shreya Das, Tanvir Noor Nafiz, Sudeep Kumar, Guangchun Bai, Hazel Dellario, Haixin Sui, Ziqiang Guan, Roy Curtiss and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Mucosal immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  7. Article
  8. Delivery ofmSphere · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Saugata MajumderDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Peng LiDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Shreya DasDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Tanvir Noor NafizDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Sudeep KumarDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Guangchun BaiDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Hazel DellarioWadsworth Center, New York State Department of Health, Albany, New York, USA.
Haixin SuiWadsworth Center, New York State Department of Health, Albany, New York, USA.
Ziqiang GuanDepartment of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA.
Roy CurtissDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Yoichi FuruyaDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA. Electronic address: y.furuya@pictordx.com.
Wei SunDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA. Electronic address: sunw@amc.edu.
Albany Medical Center Hospital · USNew York State Department of Health · USDuke Medical Center · USUniversity of Florida · US

Funding

Yersinia Outer-Membrane-Vesicle Vaccines Against Pneumonic PlagueR01AI162670 · NIAID · ALBANY MEDICAL COLLEGE · PI Wei Sun · 2022 to 2026
$3.4M
Roles of novel cationic lipids in bacterial pathogenesisR01AI178692 · NIAID · UNIVERSITY OF TEXAS DALLAS · PI Kelly S Doran, Ziqiang Guan · 2023 to 2026
$2.6M
Adaptive alterations of lipids in mitis group streptococciR01AI148366 · NIAID · UNIVERSITY OF TEXAS DALLAS · PI GUAN, ZIQIANG, PALMER, KELLI LEA · 2020 to 2024
$2.5M
Yersinia pseudotuberculosis-based vaccines for plague and yersiniosisR01AI125623 · NIAID · UNIVERSITY OF FLORIDA · PI SUN, WEI · 2016 to 2020
$2.3M
Intraflagellar transport process in primary cilium maintenanceR01GM143223 · NIGMS · WADSWORTH CENTER · PI SUI, HAIXIN · 2021 to 2024
$1.5M
Strategies to enhance mucosal vaccinationR56AI146434 · NIAID · ALBANY MEDICAL COLLEGE · PI SUN, WEI · 2019 to 2019
$403k
NIAID NIH HHS R01 AI125623NIAID NIH HHS R01 AI148366NIAID NIH HHS R01 AI162670NIAID NIH HHS R01 AI178692NIAID NIH HHS R56 AI146434NIGMS NIH HHS R01 GM143223
6 · The paper itself

Abstract

Streptococcus pneumoniae (Spn) is a common pathogen causing a secondary bacterial infection following influenza, which leads to severe morbidity and mortality during seasonal and pandemic influenza. Therefore, there is an urgent need to develop bacterial vaccines that prevent severe post-influenza bacterial pneumonia. Here, an improved Yersinia pseudotuberculosis strain (designated as YptbS46) possessing an Asd

Indexed as

Influenza, HumanInfluenza VaccinesPneumococcal InfectionsAnimalsAntibodies, BacterialBacterial ProteinsBacterial VaccinesHumansMiceMice, Inbred BALB CPneumococcal VaccinesStreptococcus pneumoniaeAntibodies, BacterialBacterial ProteinsBacterial VaccinesInfluenza VaccinesPneumococcal Vaccines

Identifiers

PMID38215909
PMCPMC11033695
OpenAlexW4390741758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.